MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Intrinsic antiviral immunity refers to a form of innate immunity that directly restricts viral
replication and assembly, thereby rendering a cell nonpermissive to a specific class or …

Exosomes are nano-sized vesicles produced by healthy and virus-infected cells. Exosomes
derived from infected cells have been shown to contain viral microRNAs (miRNAs). HIV-1 …

Toll-like receptors (TLRs) in innate immune cells are the prime cellular sensors for microbial
components. TLR activation leads to the production of proinflammatory mediators and thus …

Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites.
Indeed, they must cleverly exploit various compartments of host cells to complete their life …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading
cause of cognitive and behavioral impairment in industrialized societies. The cause of AD is …

B-cell translocation gene 2 (BTG2), the first gene identified in the BTG/TOB gene family, is
involved in many biological activities in cancer cells acting as a tumor suppressor. The BTG2 …

Background Lots of studies have shown that cyclin disorders can promote tumor
development. This study aims to investigate the biological function and molecular …

Analyses of small RNA expression profiles have revealed that several DNA viruses—
including particularly, herpesviruses—express high levels of multiple viral microRNAs …

Simian virus 40 (SV40) is a small DNA tumor virus of monkey origin. This polyomavirus was
administered to human populations mainly through contaminated polio vaccines, which …