Life and health span can be prolonged by calorie limitation or by pharmacologic agents that
mimic the effects of caloric restriction. Both starvation and the genetic inactivation of nutrient …

Apart from being a safe, effective and globally affordable glucose-lowering agent for the
treatment of diabetes, metformin has earned much credit in recent years as a potential anti …

Hormesis implies that the effects of various materials or conditions that organisms are
exposed to, may not have linear dose-response characteristics but rather, can be biphasic …

HIV‐1 infects lymphoid and myeloid cells, which can harbor a latent proviral reservoir
responsible for maintaining lifelong infection. Glycolytic metabolism has been identified as a …

Cellular adaptation to environmental stress relies on a wide range of tightly controlled
regulatory mechanisms, including transcription. Changes in chromatin structure and …

Periodontitis is a chronic infectious disease involving periodontal tissues. Periodontal
ligament cells (PDLCs) play an important role in the regeneration of periodontal tissue …

The high antibiotic resistance of Pseudomonas aeruginosa (PA) makes it critical to develop
alternative antimicrobial agents that are effective and affordable. One of the many …

Biological effects of extremely low-frequency magnetic field (ELF-MF) and its consequences
on human health have become the subject of important and recurrent public debate. ELF-MF …

Accumulating evidence now shows that supplemental antioxidants including vitamin C,
vitamin E and N-Acetylcysteine consumption can suppress adaptations to endurance-type …

Cellular adaptive mechanisms emerging after exposure to low levels of toxic agents or
stressful stimuli comprise an important biological feature that has gained considerable …