Effects and mechanisms of resveratrol on aging and age‐related diseases

DD Zhou, M Luo, SY Huang, A Saimaiti… - Oxidative medicine …, 2021 - Wiley Online Library
The aging of population has become an issue of great concern because of its rapid
increase. Aging is an important risk factor of many chronic diseases. Resveratrol could be …

[HTML][HTML] Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights

SA Mason, AJ Trewin, L Parker, GD Wadley - Redox biology, 2020 - Elsevier
Antioxidant supplements are commonly consumed by endurance athletes to minimize
exercise-induced oxidative stress, with the intention of enhancing recovery and improving …

Key signaling pathways in aging and potential interventions for healthy aging

M Yu, H Zhang, B Wang, Y Zhang, X Zheng, B Shao… - Cells, 2021 - mdpi.com
Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …

Mitochondria initiate and regulate sarcopenia

SE Alway, JS Mohamed, MJ Myers - Exercise and sport sciences …, 2017 - journals.lww.com
Sarcopenia is associated with increased levels of apoptosis (47) and reduced capabilities
for muscle regeneration (41) leading to muscle wasting. For this reason, many studies …

Resveratrol reverses the Warburg effect by targeting the pyruvate dehydrogenase complex in colon cancer cells

E Saunier, S Antonio, A Regazzetti, N Auzeil… - Scientific reports, 2017 - nature.com
Resveratrol (RES), a polyphenol found in natural foods, displays anti-oxidant, anti-
inflammatory and anti-proliferative properties potentially beneficial in cancers, in particular in …

Polyphenols and their potential role in preventing skeletal muscle atrophy

S Salucci, E Falcieri - Nutrition Research, 2020 - Elsevier
Skeletal muscle atrophy is the consequence of various conditions, such as disuse,
denervation, fasting, aging, and disease. Even if the underlying molecular mechanisms are …

SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury

Y Cheng, S Di, C Fan, L Cai, C Gao, P Jiang, W Hu… - Apoptosis, 2016 - Springer
Ischemia reperfusion (IR) injury is harmful to skeletal muscles and causes mitochondrial
oxidative stress. Pterostilbene (PTE), an analogue of resveratrol, has organic protective …

Regulation of apoptosis and autophagy in mouse and human skeletal muscle with aging and lifelong exercise training

MM Dethlefsen, JF Halling, HD Møller… - Experimental …, 2018 - Elsevier
Exercise training has been reported to prevent the age-induced decline in muscle mass and
fragmentation of mitochondria, as well as to affect autophagy and mitophagy. The interaction …

Resveratrol induces apoptosis and inhibits adipogenesis by stimulating the SIRT1-AMPKα-FOXO1 signalling pathway in bovine intramuscular adipocytes

X Liu, H Zhao, Q Jin, W You, H Cheng, Y Liu… - Molecular and cellular …, 2018 - Springer
Sirtuin type 1 (SIRTl) and AMP-activated protein kinase (AMPK) play important roles in
regulating energy metabolism, cell proliferation and differentiation, ageing, apoptosis, and …

Dietary resveratrol confers apoptotic resistance to oxidative stress in myoblasts

S Haramizu, S Asano, DC Butler, DA Stanton… - The Journal of nutritional …, 2017 - Elsevier
High levels of reactive oxygen species (ROS) contribute to muscle cell death in aging and
disuse. We have previously found that resveratrol can reduce oxidative stress in response to …