Metabolic syndrome and PCOS: Pathogenesis and the role of metabolites

W Chen, Y Pang - Metabolites, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases among
women of reproductive age and is associated with many metabolic manifestations, such as …

Nonalcoholic fatty liver disease: modulating gut microbiota to improve severity?

J Aron-Wisnewsky, MV Warmbrunn, M Nieuwdorp… - Gastroenterology, 2020 - Elsevier
Gut microbiota plays a role in the pathophysiology of metabolic diseases, which include
nonalcoholic fatty liver diseases, through the gut–liver axis. To date, clinical guidelines …

Anti-inflammatory mechanisms of polyphenols in adipose tissue: Role of gut microbiota, intestinal barrier integrity and zinc homeostasis

T Islam, K Albracht-Schulte, L Ramalingam… - The Journal of …, 2023 - Elsevier
Obesity is associated with an imbalance of micro-and macro-nutrients, gut dysbiosis, and a
“leaky” gut phenomenon. Polyphenols, such as curcumin, resveratrol, and anthocyanins …

Circulating sphingolipids and glucose homeostasis: an update

S Ali-Berrada, J Guitton, S Tan-Chen… - International Journal of …, 2023 - mdpi.com
Sphingolipids are a family of lipid molecules produced through different pathways in
mammals. Sphingolipids are structural components of membranes, but in response to …

[HTML][HTML] Ceramide-mediated gut dysbiosis enhances cholesterol esterification and promotes colorectal tumorigenesis in mice

Y Zhu, L Gu, X Lin, J Zhang, Y Tang, X Zhou, B Lu… - JCI insight, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) severely threatens human health and life span. An effective
therapeutic strategy has not been established because we do not clearly know its …

Bacteria and methanogens in the human microbiome: a review of syntrophic interactions

K Djemai, M Drancourt, M Tidjani Alou - Microbial ecology, 2022 - Springer
Methanogens are microorganisms belonging to the Archaea domain and represent the
primary source of biotic methane. Methanogens encode a series of enzymes which can …

LC/MS-based untargeted metabolomics analysis in women with morbid obesity and associated type 2 diabetes mellitus

T Auguet, L Bertran, J Capellades, S Abelló… - International Journal of …, 2023 - mdpi.com
Obesity is a chronic and complex disease, with an increasing incidence worldwide that is
associated with metabolic disorders such as type 2 diabetes mellitus (T2DM). Thus, it is …

The gut/lung microbiome axis in obesity, asthma, and bariatric surgery: a literature review

YJ Kim, JT Womble, CK Gunsch, JL Ingram - Obesity, 2021 - Wiley Online Library
Mounting evidence suggests that obesity, parameters of metabolic syndrome, and asthma
are significantly associated. Interestingly, these conditions are also associated with …

Virtual populations for quantitative systems pharmacology models

Y Cheng, R Straube, AE Alnaif, L Huang, TA Leil… - Systems Medicine, 2022 - Springer
Quantitative systems pharmacology (QSP) places an emphasis on dynamic systems
modeling, incorporating considerations from systems biology modeling and …

A divergent selection on breast meat ultimate pH, a key factor for chicken meat quality, is associated with different circulating lipid profiles

S Beauclercq, S Mignon-Grasteau, A Petit… - Frontiers in …, 2022 - frontiersin.org
Background: Chicken meat has become a major source of protein for human consumption.
However, the quality of the meat is not yet under control, especially since pH values that are …