Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …

Mitochondria are organelles with a highly dynamic ultrastructure maintained by a delicate
equilibrium between its fission and fusion rates. Understanding the factors influencing this …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Mitochondrial dysfunction is now recognized as a contributing factor to the early pathology of
multiple human conditions including neurodegenerative diseases. Mitochondria are …

As the population ages, the incidence of neurodegenerative diseases is increasing. Due to
intensive research, important steps in the elucidation of pathogenetic cascades have been …

Neurons and glia maintain central nervous system (CNS) homeostasis through diverse
mechanisms of intra-and intercellular signaling. Some of these interactions include the …

Mitochondria are multifunctional organelles that not only produce energy for the cell, but are
also important for cell signalling, apoptosis and many biosynthetic pathways. In most cell …

ABSTRACT Cytoplasmic dynein-1 (hereafter dynein) is an essential cellular motor that
drives the movement of diverse cargos along the microtubule cytoskeleton, including …

The orchestration of intercellular communication is essential for multicellular organisms. One
mechanism by which cells communicate is through long, actin-rich membranous protrusions …

Background Alzheimer's disease (AD) is the most prevalent form of dementia worldwide and
is characterized by progressive memory loss and cognitive impairment. Our understanding …