Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data

AL Hicks, N Wheeler, L Sánchez-Busó… - PLoS computational …, 2019 - journals.plos.org
Prediction of antibiotic resistance phenotypes from whole genome sequencing data by
machine learning methods has been proposed as a promising platform for the development …

VAMPr: VA riant M apping and P rediction of antibiotic r esistance via explainable features and machine learning

J Kim, DE Greenberg, R Pifer, S Jiang… - PLoS computational …, 2020 - journals.plos.org
Antimicrobial resistance (AMR) is an increasing threat to public health. Current methods of
determining AMR rely on inefficient phenotypic approaches, and there remains incomplete …

Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics

AL Hicks, SM Kissler, M Lipsitch, YH Grad - PLoS Biology, 2019 - journals.plos.org
The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is
limited by the extent to which they detect genes and alleles that lead to resistance. As novel …

Multiple phylogenetically-diverse, differentially-virulent Burkholderia pseudomallei isolated from a single soil sample collected in Thailand

C Roe, AJ Vazquez, PD Phillips… - PLoS neglected …, 2022 - journals.plos.org
Burkholderia pseudomallei is a soil-dwelling bacterium endemic to Southeast Asia and
northern Australia that causes the disease, melioidosis. Although the global genomic …

Precise prediction of antibiotic resistance in Escherichia coli from full genome sequences

D Moradigaravand, M Palm, A Farewell, V Mustonen… - bioRxiv, 2018 - biorxiv.org
The emergence of microbial antibiotic resistance is a global health threat. In clinical settings,
the key to controlling spread of resistant strains is accurate and rapid detection. As …

[PDF][PDF] Computational and Structural Biotechnology Reports

P Mohseni, A Ghorbani - researchgate.net
The integration of artificial intelligence (AI) into microbiology has the transformative potential
to advance our understanding and treatment of microbial systems. This review examines …

[引用][C] VAMPr: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning 2

AK Shelburne, Y Xie, X Zhan