Four principles to establish a universal virus taxonomy
A universal taxonomy of viruses is essential for a comprehensive view of the virus world and
for communicating the complicated evolutionary relationships among viruses. However …
for communicating the complicated evolutionary relationships among viruses. However …
Investigations on the interface of nucleic acid aptamers and binding targets
S Cai, J Yan, H Xiong, Y Liu, D Peng, Z Liu - Analyst, 2018 - pubs.rsc.org
Nucleic acid aptamers are single-stranded DNA or RNA of 20–100 nucleotides in length that
have attracted substantial scientific interest due to their ability to specifically bind to target …
have attracted substantial scientific interest due to their ability to specifically bind to target …
Mechanisms of bacterial transcription termination: all good things must end
A Ray-Soni, MJ Bellecourt… - Annual review of …, 2016 - annualreviews.org
Transcript termination is essential for accurate gene expression and the removal of RNA
polymerase (RNAP) at the ends of transcription units. In bacteria, two mechanisms are …
polymerase (RNAP) at the ends of transcription units. In bacteria, two mechanisms are …
Second harmonic generation microscopy: a powerful tool for bio-imaging
Second harmonic generation (SHG) microscopy is an important optical imaging technique in
a variety of applications. This article describes the history and physical principles of SHG …
a variety of applications. This article describes the history and physical principles of SHG …
EMDataBank unified data resource for 3DEM
CL Lawson, A Patwardhan, ML Baker… - Nucleic acids …, 2016 - academic.oup.com
Abstract Three-dimensional Electron Microscopy (3DEM) has become a key experimental
method in structural biology for a broad spectrum of biological specimens from molecules to …
method in structural biology for a broad spectrum of biological specimens from molecules to …
Current strategies for protein production and purification enabling membrane protein structural biology
Membrane proteins are still heavily under-represented in the protein data bank (PDB),
owing to multiple bottlenecks. The typical low abundance of membrane proteins in their …
owing to multiple bottlenecks. The typical low abundance of membrane proteins in their …
Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations
Protein conformational changes are at the heart of cell functions, from signalling to ion
transport. However, the transient nature of the intermediates along transition pathways …
transport. However, the transient nature of the intermediates along transition pathways …
PRIMO: An interactive homology modeling pipeline
R Hatherley, DK Brown, M Glenister, Ö Tastan Bishop - PLoS One, 2016 - journals.plos.org
The development of automated servers to predict the three-dimensional structure of proteins
has seen much progress over the years. These servers make calculations simpler, but …
has seen much progress over the years. These servers make calculations simpler, but …
[PDF][PDF] Refinement of organic crystal structures with multipolar electron scattering factors
B Gruza, ML Chodkiewicz… - … A: Foundations and …, 2020 - journals.iucr.org
A revolution in resolution is occurring now in electron microscopy arising from the
development of methods for imaging single particles at cryogenic temperatures and …
development of methods for imaging single particles at cryogenic temperatures and …
Structure prediction of self-assembled dye aggregates from cryogenic transmission electron microscopy, molecular mechanics, and theory of optical spectra
C Friedl, T Renger, H Berlepsch, K Ludwig… - The Journal of …, 2016 - ACS Publications
Cryogenic transmission electron microscopy (cryo-TEM) studies suggest that TTBC
molecules self-assemble in aqueous solution to form single-walled tubes with a diameter of …
molecules self-assemble in aqueous solution to form single-walled tubes with a diameter of …