Psoriasis is an immune-mediated systemic disease with associated comorbidities, including
metabolic syndrome (MetS) which contributes substantially to premature mortality in patients …

Obesity is a major public health issue worldwide since it is associated with the development
of chronic comorbidities such as type 2 diabetes, dyslipidemias, atherosclerosis, some …

Psoriasis is a chronic and immune-mediated skin condition characterized by pro-
inflammatory cytokines and keratinocyte hyperproliferation. Dendritic cells, T lymphocytes …

Interleukin-17 (IL-17) family cytokines are potent drivers of inflammatory responses.
Although IL-17 was originally identified as a cytokine that induces protective effects against …

Obesity is closely related to dyslipidaemia, diabetes and other metabolic syndromes. Long‐
term consumption of a high‐fat diet (HFD) is an important risk factor that can lead to obesity …

Psoriasis, an autoimmune chronic inflammatory skin condition, has a high incidence in the
general population, reaching 2–4%. Its pathogenesis involves an interplay of genetic factors …

Psoriasis is an immune-mediated inflammatory skin disease associated with multiple
comorbidities. Considered one of the most common inflammatory skin diseases among the …

Introduction Patients with psoriatic arthritis (PsA) are frequently obese. We have previously
shown decreased disease activity in patients with PsA with a body mass index (BMI)≥ 33 …

In response to obesity-associated chronic inflammatory disorders, adipose tissue releases a
biologically active peptide known as leptin. Leptin activates the secretion of chemical …

The differential diagnosis of psoriatic arthritis (PsA) and rheumatoid arthritis (RA) is difficult
because of the lack of diagnostic clinical signs and reliable biomarkers. This study …