Breast cancer is the most common cancer in women, responsible for over half a million
deaths in 2020. Almost 75% of FDA-approved drugs are mainly nitrogen-and sulfur …

Abstract Novel 5-amino-1, 2, 4-triazole derivatives and their cyclized 1, 2, 4-triazolo [1, 5-a]
pyrimidine analogues were designed, synthesized and evaluated for their antimicrobial …

Cancer as a devastating malignancy, seriously threatens human life and health, but most
chemotherapeutics have long been criticized for unsatisfactory therapeutic efficacy due to …

Increase in the number of infections caused by pathogenic microbes in cancer patients has
prompted the searcher to invest in the development of agents having dual anticancer and …

The antitumor activity of newly synthesized 4-anilino-2-vinylquinazolines 8a-r was measured
comparable to sorafenib as a standard drug. The 2-vinylquinazolines 8a-r were evaluated …

A new series of indoline-2-one derivatives was designed and synthesized based on the
essential pharmacophoric features of VEGFR-2 inhibitors. Anti-proliferative activities were …

An array of newly synthesized thieno [3, 2-d] pyrimidine-based derivatives and
thienotriazolopyrimidines hybridized with some pharmacophoric anticancer fragments were …

Non-small cell Lung cancer (NSCLC) is the most common type of lung cancer, which is
caused by high consumption of tobacco and smoking. It is an epithelial lung cancer that …

Thiazole and its derivatives have received a lot of attention from researchers due to its wide
biological, pharmacological, and anticancer properties. A novel series of 2-[2-[4-Hydroxy-3 …

Abstract Newly designed 4-aminoquinazoline derivatives (5a-f, 6a, b, 7, 8, 9, 10a-c, 11a, b,
12a, b and 13a, b) have been synthesized and evaluated for their potential multitarget …