Background Macrophages are a critical component of the innate immune system, derived
from monocytes, with significant roles in anti-inflammatory and anti-tumour activities. In the …

Allergic inflammation of the airways such as allergic asthma is a major health problem with
growing incidence world-wide. One cardinal feature in severe type 2-dominated airway …

Designing a novel nanoplatform that integrates multimodal imaging and synergistic therapy
for precision tumor nanomedicines is challenging. Herein, we prepared rare-earth ion …

Klebsiella pneumoniae is a primary cause of community-acquired and nosocomial
respiratory infections, and K. pneumoniae resistance to the current treatment approach with …

Foot and mouth disease (FMD) is a highly contagious infection caused by FMD-virus
(FMDV) that affects livestock worldwide with significant economic impact. The main strategy …

Objective SKG mice develop interstitial lung disease (ILD) resembling rheumatoid arthritis–
associated ILD in humans. The aim of this study was to clarify the mechanism underlying the …

Background IFN-γ is a key mediator of tumor immunity that can induce macrophage
polarization to suppress tumor growth. Cyclin G2 functions as a tumor suppressor in various …

Fluorouracil (5-FU) is an analog of pyrimidine and has been shown to display antitumor and
immunomodulatory effects. However, the impacts of 5-FU in regulating asthma, an …

Dengue fever is a global health threat caused by the dengue virus (DENV), a vector-borne
and single-stranded RNA virus. Development of a safe and efficacious vaccine against …

Macrophages and dendritic cells (DCs) are innate immune cells that play a key role in
defense against pathogens. In vitro cultures of bone marrow-derived macrophages …