BACKGROUND Interstitial lung disease (ILD) is the leading cause of morbidity and mortality
in patients with systemic sclerosis (SSc); however, prognostication of SSc-associated ILD …

Systemic sclerosis (SSc) is a rare multisystem autoimmune disease, characterized by
fibrosis, vasculopathy, and autoimmunity. Recent advances have highlighted the significant …

Systemic sclerosis (SSc) has the highest cause-specific mortality of all the connective tissue
diseases, and the aetiology of this complex and heterogeneous condition remains an …

Objectives To assess the long-term efficacy and safety of single and multiple courses of
rituximab therapy in systemic sclerosis (SSc) patients with and without lung disease …

Objectives Scleroderma heart disease is a major risk of death in systemic sclerosis (SSc).
Mechanisms underlying myocardial damage are still unclear. We performed an extensive …

Systemic sclerosis is an autoimmune disease leading to vasculopathy and fibrosis of skin
and internal organs. Despite likely shared pathogenic mechanisms, the patterns of skin and …

Contemporary studies of systemic sclerosis consistently demonstrate that interstitial lung
disease is a leading cause of disease-related death. This review summarizes morbidity and …

Interstitial lung disease (ILD) is the leading cause of morbidity and mortality in systemic
sclerosis (SSc). We performed a systematic review to characterise the use and validation of …

Objective. To identify predictors of poor prognosis in patients with systemic sclerosis (SSc)
associated with interstitial lung disease (ILD). Methods. Fifty patients with early-stage SSc …

Systemic sclerosis (SSc) is a chronic systemic disease within the spectrum of connective
tissue diseases, specifically characterized by vascular abnormalities and inflammatory and …