New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN

A Monteil, NC Guérineau, A Gil-Nagel… - Physiological …, 2024 - journals.physiology.org
Cell excitability and its modulation by hormones and neurotransmitters involve the concerted
action of a large repertoire of membrane proteins, especially ion channels. Unique …

Uterine excitability and ion channels and their changes with gestation and hormonal environment

S Wray, S Arrowsmith - Annual review of physiology, 2021 - annualreviews.org
We address advances in the understanding of myometrial physiology, focusing on excitation
and the effects of gestation on ion channels and their relevance to labor. This review moves …

Uterine contractions in rodent models and humans

M Malik, M Roh, SK England - Acta physiologica, 2021 - Wiley Online Library
Aberrant uterine contractions can lead to preterm birth and other labour complications and
are a significant cause of maternal morbidity and mortality. To investigate the mechanisms …

Volatile anesthetics activate a leak sodium conductance in retrotrapezoid nucleus neurons to maintain breathing during anesthesia in mice

Y Yang, M Ou, J Liu, W Zhao, L Zhuoma… - …, 2020 - pmc.ncbi.nlm.nih.gov
Background: Volatile anesthetics moderately depress respiratory function at clinically
relevant concentrations. Phox2b-expressing chemosensitive neurons in the retrotrapezoid …

Modeling and experimental approaches for elucidating multi-scale uterine smooth muscle electro-and mechano-physiology: A review

AS Garrett, SA Means, MW Roesler, KJW Miller… - Frontiers in …, 2022 - frontiersin.org
The uterus provides protection and nourishment (via its blood supply) to a developing fetus,
and contracts to deliver the baby at an appropriate time, thereby having a critical contribution …

Whole-exome sequencing reveals candidate high-risk susceptibility genes for endometriosis

S Nousiainen, O Kuismin, S Reinikka, R Manninen… - Human Genomics, 2023 - Springer
Background Endometriosis is a common, chronic disease among fertile-aged women.
Disease course may be highly invasive, requiring extensive surgery. The etiology of …

The physiological basis with uterine myometrium contractions from electro-mechanical/hormonal myofibril function to the term and preterm labor

FZ Zangeneh, S Hantoushzadeh - Heliyon, 2023 - cell.com
Background Most labor-related problems can be attributed to the uterine myometrium
muscle, as this irritable tissue must suppress its irritability potential during pregnancy …

Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells

C Amazu, X Ma, C Henkes, JJ Ferreira… - American Journal …, 2020 - journals.physiology.org
During pregnancy, the uterus transitions from a quiescent state to an excitable, highly
contractile state to deliver the fetus. Two important contributors essential for this transition …

Adiponectin and Glucocorticoids Modulate Risk for Preterm Birth: The Healthy Start Study

G Mayne, PE DeWitt, J Wen… - The Journal of …, 2025 - academic.oup.com
Context Adiponectin is a potent uterine tocolytic that decreases with gestational age,
suggesting it could be a maternal metabolic quiescence factor. Maternal stress can influence …

Managerial extraversion and corporate voluntary disclosure

F Eugster, J Kallunki, JP Kallunki… - Contemporary …, 2024 - Wiley Online Library
This article examines the effect of managers' personality trait of extraversion on the voluntary
disclosure of their firms. Our results from analyzing archival data from Sweden show that the …