The KCNH family of ion channels, comprising ether-à-go-go (EAG), EAG-related gene
(ERG), and EAG-like (ELK) K+-channel subfamilies, is crucial for repolarization of the …

KV10. 1 has recently become generally accepted as a promising cancer target, as it is
ectopically expressed in the majority of solid tumors. Due to its cell-surface accessibility …

Ether-à-go-go1 (Eag1, Kv10. 1, KCNH1) K+ channel is a member of the voltage‐gated K+
channel family mainly distributed in the central nervous system and cancer cells. Like other …

Calcium in the flagellum controls sperm navigation. In sperm of marine invertebrates and
mammals, Ca2+ signalling has been intensely studied, whereas for fish little is known. In …

Multidrug resistance (MDR) occurs when bacteria simultaneously acquire resistance to a
broad spectrum of structurally dissimilar compounds to which they have not previously been …

The ability to coordinate behavioral responses with metabolic status is fundamental to the
maintenance of energy homeostasis. In numerous species including Caenorhabditis …

The voltage-gated, K+-selective ether á go-go 1 (EAG1) channel is expressed throughout
the brain where it is thought to regulate neuronal excitability. Besides its normal …

Human Ether á go-go Related Gene potassium channels form the rapid component of the
delayed-rectifier (IKr) current in the heart. The N-terminal 'eag'domain, which is composed of …

The human ERG (hERG) K+ channel has a crucial function in cardiac repolarization, and
mutations or channel block can give rise to long QT syndrome and catastrophic ventricular …

The hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels are
pacemaker channels whose currents contribute to rhythmic activity in the heart and brain …