Protein–protein interaction and quaternary structure
Protein–protein recognition plays an essential role in structure and function. Specific non-
covalent interactions stabilize the structure of macromolecular assemblies, exemplified in …
covalent interactions stabilize the structure of macromolecular assemblies, exemplified in …
PRODIGY: a web server for predicting the binding affinity of protein–protein complexes
Gaining insights into the structural determinants of protein–protein interactions holds the key
for a deeper understanding of biological functions, diseases and development of …
for a deeper understanding of biological functions, diseases and development of …
Targeting tumors using peptides
P Scodeller, EK Asciutto - Molecules, 2020 - mdpi.com
To penetrate solid tumors, low molecular weight (Mw< 10 KDa) compounds have an edge
over antibodies: their higher penetration because of their small size. Because of the dense …
over antibodies: their higher penetration because of their small size. Because of the dense …
Transport mechanism of a bacterial homologue of glutamate transporters
N Reyes, C Ginter, O Boudker - Nature, 2009 - nature.com
Glutamate transporters are integral membrane proteins that catalyse a thermodynamically
uphill uptake of the neurotransmitter glutamate from the synaptic cleft into the cytoplasm of …
uphill uptake of the neurotransmitter glutamate from the synaptic cleft into the cytoplasm of …
Structure and activity of lysozyme on binding to ZnO nanoparticles
S Chakraborti, T Chatterjee, P Joshi, A Poddar… - Langmuir, 2010 - ACS Publications
The interaction between ZnO nanoparticles (NPs) and lysozyme has been studied using
calorimetric as well as spectrophotometric techniques, and interpreted in terms of the three …
calorimetric as well as spectrophotometric techniques, and interpreted in terms of the three …
Secondary structure based analysis and classification of biological interfaces: identification of binding motifs in protein–protein interactions
M Guharoy, P Chakrabarti - Bioinformatics, 2007 - academic.oup.com
Motivation: The increasing amount of data on protein–protein interaction needs to be
rationalized for deriving guidelines for the alteration or design of an interface between two …
rationalized for deriving guidelines for the alteration or design of an interface between two …
A survey of available tools and web servers for analysis of protein–protein interactions and interfaces
The unanimous agreement that cellular processes are (largely) governed by interactions
between proteins has led to enormous community efforts culminating in overwhelming …
between proteins has led to enormous community efforts culminating in overwhelming …
The DNA-binding domain mediates both nuclear and cytosolic functions of p53
Under conditions of genotoxic stress, human p53 activates the apoptotic effectors BAX or
BAK to result in mitochondrial outer-membrane permeabilization and apoptosis …
BAK to result in mitochondrial outer-membrane permeabilization and apoptosis …
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
M Guharoy, P Chakrabarti - BMC bioinformatics, 2010 - Springer
Background Biological evolution conserves protein residues that are important for structure
and function. Both protein stability and function often require a certain degree of structural co …
and function. Both protein stability and function often require a certain degree of structural co …
Copper (I)-mediated protein–protein interactions result from suboptimal interaction surfaces
L Banci, I Bertini, V Calderone… - Biochemical …, 2009 - portlandpress.com
The homoeostasis of metal ions in cells is the result of the contribution of several cellular
pathways that involve transient, often weak, protein–protein interactions. Metal transfer …
pathways that involve transient, often weak, protein–protein interactions. Metal transfer …