[HTML][HTML] Etiopathogenesis of ovarian cancer. An inflamm-aging entity?

M Sánchez-Prieto, R Sánchez-Borrego… - Gynecologic Oncology …, 2022 - Elsevier
Ovarian cancer is one of the most common gynecologic cancers and has the highest
mortality rate. The risk/protective factors of ovarian cancer suggest that its etiology is …

The mechanistic immunosuppressive role of the tumour vasculature and potential nanoparticle-mediated therapeutic strategies

ZE Ileiwat, TA Tabish, DA Zinovkin… - Frontiers in …, 2022 - frontiersin.org
The tumour vasculature is well-established to display irregular structure and hierarchy that is
conducive to promoting tumour growth and metastasis while maintaining …

Pro-tumorigenic role of type 2 diabetes-induced cellular senescence in colorectal cancer

F Melia, P Udomjarumanee, D Zinovkin… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide.
The disease still remains incurable and highly lethal in the advanced stage, representing a …

Dicarbonyl stress debilitates mesothelial defense against metastasizing ovarian cancer

S Mishra, K Vidhipriya, A Gopikrishnan, S Mishra… - bioRxiv, 2024 - biorxiv.org
Chronic metabolic disorders and aging result in accumulation of active dicarbonyls that
glycate biomolecules rendering them dysfunctional. Although metabolic aberrations are …