[HTML][HTML] Deciphering the astrocyte reaction in Alzheimer's disease

BG Perez-Nievas, A Serrano-Pozo - Frontiers in Aging Neuroscience, 2018 - frontiersin.org
Reactive astrocytes were identified as a component of senile amyloid plaques in the cortex
of Alzheimer's disease (AD) patients several decades ago. However, their role in AD …

Coxsackievirus B3 replication and pathogenesis

FS Garmaroudi, D Marchant, R Hendry, H Luo… - Future …, 2015 - Taylor & Francis
Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites.
Indeed, they must cleverly exploit various compartments of host cells to complete their life …

NF-κB signaling is key in the wound healing processes of silk fibroin

YR Park, MT Sultan, HJ Park, JM Lee, HW Ju, OJ Lee… - Acta biomaterialia, 2018 - Elsevier
Silk fibroin (SF) is a well-studied biomaterial for tissue engineering applications including
wound healing. However, the signaling mechanisms underlying the impact of SF on this …

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

J Li, Y Tang, D Cai - Nature cell biology, 2012 - nature.com
Adult neural stem cells (NSCs) are known to exist in a few regions of the brain; however, the
entity and physiological/disease relevance of adult hypothalamic NSCs (htNSCs) remain …

NF-κB signaling, liver disease and hepatoprotective agents

B Sun, M Karin - Oncogene, 2008 - nature.com
The NF-κB signaling pathway has particular relevance to several liver diseases including
hepatitis (liver infection by Helicobacter, viral hepatitis induced by HBV and HCV), liver …

Antioxidant silk fibroin composite hydrogel for rapid healing of diabetic wound

B Maity, S Alam, S Samanta… - Macromolecular …, 2022 - Wiley Online Library
Wound healing is a complex process requiring multiple biological pathways and chemical
responses to be activated and synchronized to recover tissue integrity. In normal …

HPV E6/E7: insights into their regulatory role and mechanism in signaling pathways in HPV-associated tumor

Q Peng, L Wang, L Zuo, S Gao, X Jiang, Y Han… - Cancer gene …, 2024 - nature.com
Human papillomavirus (HPV) is a class of envelope-free double-stranded DNA virus. HPV
infection has been strongly associated with the development of many malignancies, such as …

A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo

KB Harikumar, AB Kunnumakkara, N Ochi, Z Tong… - Molecular cancer …, 2010 - AACR
Protein kinase D (PKD) family members are increasingly implicated in multiple normal and
abnormal biological functions, including signaling pathways that promote mitogenesis in …

Neurotoxic effects of 2-ethylhexyl diphenyl phosphate exposure on zebrafish larvae: Insight into inflammation-driven changes in early motor behavior

A Ni, L Fang, M Xi, J Li, Q Qian, Z Wang, X Wang… - Science of The Total …, 2024 - Elsevier
The extensive utilization and potential adverse impacts of the replacement flame-retardant 2-
Ethylhexyl Diphenyl Phosphate (EHDPP) have raised concerns. Currently, there is limited …

MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1

CYA Chen, JT Chang, YF Ho, AB Shyu - Nucleic acids research, 2016 - academic.oup.com
MiR-26 has emerged as a key tumour suppressor in various cancers. Accumulating
evidence supports that miR-26 regulates inflammation and tumourigenicity largely through …