From 2000 to mid-2010: A fruitful decade for the synthesis of pyrazoles

S Fustero, M Sánchez-Roselló, P Barrio… - Chemical …, 2011 - ACS Publications
In the past decade, interest in pyrazole chemistry has significatively increased mainly due to
the discovery of the interesting properties exhibited by a great number of pyrazole …

Tailor‐made amino acids and fluorinated motifs as prominent traits in modern pharmaceuticals

H Mei, J Han, S White, DJ Graham… - … A European Journal, 2020 - Wiley Online Library
Structural analysis of modern pharmaceutical practices allows for the identification of two
rapidly growing trends: the introduction of tailor‐made amino acids and the exploitation of …

Asymmetric synthesis of α-amino acids via homologation of Ni (II) complexes of glycine Schiff bases; Part 1: alkyl halide alkylations

AE Sorochinsky, JL Aceña, H Moriwaki, T Sato… - Amino Acids, 2013 - Springer
Alkylations of chiral or achiral Ni (II) complexes of glycine Schiff bases constitute a landmark
in the development of practical methodology for asymmetric synthesis of α-amino acids …

Asymmetric synthesis of α-amino acids via homologation of Ni (II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous …

JL Aceña, AE Sorochinsky, V Soloshonok - Amino Acids, 2014 - Springer
The major goal of this review is a critical discussion of the literature data on asymmetric
synthesis of α-amino acids via Michael addition reactions involving Ni (II)-complexes of …

Practical synthesis of fluorine-containing α-and β-amino acids: recipes from Kiev, Ukraine

VP Kukhar, AE Sorochinsky… - Future Medicinal …, 2009 - Taylor & Francis
Naturally occurring compounds containing a CF bond are extremely rare; only a handful of
fluorine-containing carboxylic acids have been described so far. By contrast, man-made …

Practical methods for the synthesis of symmetrically α, α-disubstituted α-amino acids

VA Soloshonok, AE Sorochinsky - Synthesis, 2010 - thieme-connect.com
This report provides an overview of the practical methods for preparing symmetrically α, α-
disubstituted α-amino acids and their derivatives. Despite the growing application of this …

Asymmetric synthesis of α-deuterated α-amino acids

R Takeda, H Abe, N Shibata, H Moriwaki… - Organic & …, 2017 - pubs.rsc.org
α-Deuterated-α-amino acids represent a very special class of stable isotopically labeled
compounds, used in advanced biomedical research. Herein, we disclose a generalized …

Understanding the mechanism of replacement of citrate from the surface of gold nanoparticles by amino acids: A theoretical and experimental investigation and their …

M Rani, L Moudgil, B Singh, A Kaushal, A Mittal… - RSC …, 2016 - pubs.rsc.org
The present study explores the physicochemical aspects needed for the appropriate in vitro
synthesis and surface modification behavior of gold nanoparticles (AuNPs) in the presence …

Analysis of crystallographic structures of Ni (ii) complexes of α-amino acid Schiff bases: elucidation of the substituent effect on stereochemical preferences

Y Nian, J Wang, H Moriwaki, VA Soloshonok… - Dalton Transactions, 2017 - pubs.rsc.org
In this study, we performed critical analysis of 13 crystallographic structures of various Ni (II)
complexes of amino acid Schiff bases. The major finding of this work is the significance of a …

Large-Scale Synthesis of the Glycine Schiff Base Ni(II) Complex Derived from (S)- and (R)-N-(2-Benzoyl-4-chlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-2 …

TT Romoff, BG Ignacio, N Mansour… - … Process Research & …, 2020 - ACS Publications
Non-natural, tailor-made amino acids are of crucial importance to the synthesis of bioactive
peptides and new chemical entities. Innovative methodology is always needed for the …