α6-Containing GABAA receptors: functional roles and therapeutic potentials
GABA A receptors containing the α6 subunit are highly expressed in cerebellar granule cells
and less abundantly in many other neuronal and peripheral tissues. Here, we for the first …
and less abundantly in many other neuronal and peripheral tissues. Here, we for the first …
[HTML][HTML] Recent progress on Tourette syndrome
K Ueda, KJ Black - Faculty Reviews, 2021 - ncbi.nlm.nih.gov
Tic disorders and Tourette syndrome are the most common movement disorders in children
and are characterized by movements or vocalizations. Clinically, Tourette syndrome is …
and are characterized by movements or vocalizations. Clinically, Tourette syndrome is …
Neuroanatomical signatures associated with dispositional optimism predict COVID-19-related posttraumatic stress symptoms
The COVID-19 pandemic has been increasingly documented to cause negative impacts on
mental health outcomes, eg posttraumatic stress symptoms (PTSS). Dispositional optimism …
mental health outcomes, eg posttraumatic stress symptoms (PTSS). Dispositional optimism …
The cerebellum in drug-naive children with Tourette syndrome and obsessive–compulsive disorder
Tourette syndrome (TS) and obsessive–compulsive disorder (OCD) are two
neurodevelopmental disorders characterized by repetitive behaviors. Our recent study in …
neurodevelopmental disorders characterized by repetitive behaviors. Our recent study in …
[HTML][HTML] The dysfunctional mechanisms throwing tics: structural and functional changes in Tourette syndrome
Tourette Syndrome (TS) is a high-incidence multifactorial neuropsychiatric disorder
characterized by motor and vocal tics co-occurring with several diverse comorbidities …
characterized by motor and vocal tics co-occurring with several diverse comorbidities …
Resting-state functional connectivity in drug-naive pediatric patients with Tourette syndrome and obsessive-compulsive disorder
Previous studies in cohorts of Tourette syndrome (TS) or obsessive-compulsive disorder
(OCD) patients have not clarified whether these two disorders represent two clinical …
(OCD) patients have not clarified whether these two disorders represent two clinical …
The role of the cerebellum in repetitive behavior across species: childhood stereotypies and deer mice
Recent studies suggest that the cerebellum may have a significant role in repetitive
behaviors. In primary complex motor stereotypies, typically developing children have …
behaviors. In primary complex motor stereotypies, typically developing children have …
Multivariate classification provides a neural signature of Tourette disorder
Background Tourette disorder (TD), hallmarks of which are motor and vocal tics, has been
related to functional abnormalities in large-scale brain networks. Using a fully data driven …
related to functional abnormalities in large-scale brain networks. Using a fully data driven …
Increased alpha-band connectivity during tic suppression in children with Tourette syndrome revealed by source electroencephalography analyses
Background Tourette syndrome (TS) is a neurodevelopmental disorder involving chronic
motor and phonic tics. Most individuals with TS can suppress their tics for at least a short …
motor and phonic tics. Most individuals with TS can suppress their tics for at least a short …
[HTML][HTML] Alpha6-containing GABAA receptors–Novel targets for the treatment of schizophrenia
LC Chiou, W Sieghart - Pharmacological Research, 2025 - Elsevier
Abstract α6-containing GABA A receptors (α6GABA A Rs) are strongly expressed in
cerebellar granule cells and are of central importance for cerebellar functions. The …
cerebellar granule cells and are of central importance for cerebellar functions. The …