Radiotherapy combined with immunotherapy: the dawn of cancer treatment
Z Zhang, X Liu, D Chen, J Yu - Signal Transduction and Targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
Cancer in sub-Saharan Africa: a lancet oncology commission
Summary In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in
cancer incidence and mortality. Without rapid interventions, data estimates show a major …
cancer incidence and mortality. Without rapid interventions, data estimates show a major …
STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma
As a key component of the standard of care for glioblastoma, radiotherapy induces several
immune resistance mechanisms, such as upregulation of CD47 and PD-L1. Here …
immune resistance mechanisms, such as upregulation of CD47 and PD-L1. Here …
DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer
RX Huang, PK Zhou - Signal transduction and targeted therapy, 2020 - nature.com
Radiotherapy is one of the most common countermeasures for treating a wide range of
tumors. However, the radioresistance of cancer cells is still a major limitation for …
tumors. However, the radioresistance of cancer cells is still a major limitation for …
Artificial intelligence in radiation oncology
Artificial intelligence (AI) has the potential to fundamentally alter the way medicine is
practised. AI platforms excel in recognizing complex patterns in medical data and provide a …
practised. AI platforms excel in recognizing complex patterns in medical data and provide a …
Mortality impact of achieving WHO cervical cancer elimination targets: a comparative modelling analysis in 78 low-income and lower-middle-income countries
Background WHO is developing a global strategy towards eliminating cervical cancer as a
public health problem, which proposes an elimination threshold of four cases per 100 000 …
public health problem, which proposes an elimination threshold of four cases per 100 000 …
Biomineralized MnO2 Nanoplatforms Mediated Delivery of Immune Checkpoint Inhibitors with STING Pathway Activation to Potentiate Cancer Radio-Immunotherapy
Radiotherapy (RT), as one of the main methods in the clinical treatment of various malignant
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
The Lancet NCDI Poverty Commission: bridging a gap in universal health coverage for the poorest billion
Executive summary “As we embark on this great collective journey, we pledge that no one
will be left behind. Recognizing that the dignity of the human person is fundamental, we wish …
will be left behind. Recognizing that the dignity of the human person is fundamental, we wish …
Medical imaging and nuclear medicine: a Lancet Oncology Commission
The diagnosis and treatment of patients with cancer requires access to imaging to ensure
accurate management decisions and optimal outcomes. Our global assessment of imaging …
accurate management decisions and optimal outcomes. Our global assessment of imaging …
Integrated MRI-guided radiotherapy—opportunities and challenges
MRI can help to categorize tissues as malignant or non-malignant both anatomically and
functionally, with a high level of spatial and temporal resolution. This non-invasive imaging …
functionally, with a high level of spatial and temporal resolution. This non-invasive imaging …