Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

[HTML][HTML] Global colorectal cancer burden in 2020 and projections to 2040

Y Xi, P Xu - Translational oncology, 2021 - Elsevier
As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …

Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer

LA Rojas, Z Sethna, KC Soares, C Olcese, N Pang… - Nature, 2023 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is lethal in 88% of patients, yet harbours
mutation-derived T cell neoantigens that are suitable for vaccines,. Here in a phase I trial of …

Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN

E Morgan, M Arnold, A Gini, V Lorenzoni, CJ Cabasag… - Gut, 2023 - gut.bmj.com
Objective Colorectal cancer (CRC) is the third most common cancer worldwide. The
geographical and temporal burden of this cancer provides insights into risk factor …

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

BS Sheena, L Hiebert, H Han, H Ippolito… - The lancet …, 2022 - thelancet.com
Background Combating viral hepatitis is part of the UN Sustainable Development Goals
(SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector …

[HTML][HTML] The European cancer burden in 2020: Incidence and mortality estimates for 40 countries and 25 major cancers

T Dyba, G Randi, F Bray, C Martos, F Giusti… - European Journal of …, 2021 - Elsevier
Introduction Europe is an important focus for compiling accurate and up-to-date world
cancer statistics owing to its large share of the world's total cancer burden. This article …

[HTML][HTML] Epidemiology of stomach cancer

M Ilic, I Ilic - World journal of gastroenterology, 2022 - ncbi.nlm.nih.gov
Despite a decline in incidence and mortality during the last decades, stomach cancer is one
of the main health challenges worldwide. According to the GLOBOCAN 2020 estimates …

Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors

AP Klein - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Pancreatic cancer is a leading cause of cancer death worldwide and its global burden has
more than doubled over the past 25 years. The highest incidence regions for pancreatic …

[HTML][HTML] Pancreatic cancer: A review of epidemiology, trend, and risk factors

JX Hu, CF Zhao, WB Chen, QC Liu, QW Li… - World journal of …, 2021 - ncbi.nlm.nih.gov
Despite rapid advances in modern medical technology and significant improvements in
survival rates of many cancers, pancreatic cancer is still a highly lethal gastrointestinal …

Global, regional, and national cancer incidence and death for 29 cancer groups in 2019 and trends analysis of the global cancer burden, 1990–2019

L Lin, Z Li, L Yan, Y Liu, H Yang, H Li - Journal of hematology & oncology, 2021 - Springer
Background and aims Cancer will soon become the leading cause of death in every country
in the twenty-first century. This study aimed to analyze the mortality and morbidity of 29 types …