Heavy alcohol use is the cause of alcoholic liver disease (ALD). The ALD spectrum ranges
from alcoholic steatosis to steatohepatitis, fibrosis, and cirrhosis. In Western countries …

Alcohol-associated liver disease (ALD) represents a spectrum of liver injury resulting from
alcohol use, ranging from hepatic steatosis to more advanced forms including alcoholic …

Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

Prediction of hepatocellular carcinoma (HCC) risk is an urgent unmet need in patients with
nonalcoholic fatty liver disease (NAFLD). In cohorts of 409 patients with NAFLD from …

Background Accurate non-invasive prediction of long-term hepatocellular carcinoma (HCC)
risk in advanced liver fibrosis is urgently needed for cost-effective HCC screening; however …

Chronic liver disease and hepatocellular carcinoma (HCC) are life-threatening diseases
with limited treatment options. The lack of clinically relevant/tractable experimental models …

Cancer driver gene alterations influence cancer development, occurring in oncogenes,
tumor suppressors, and dual role genes. Discovering dual role cancer genes is difficult …

Objective Alcohol-related liver disease (ALD) ranges from never-decompensated ALD
(ndALD) to the life-threatening decompensated phenotype, known as alcohol-related …

Hepatocellular carcinoma (HCC) has high recurrence rates even after curative hepatectomy.
Drug therapy for recurrence of HCC is still limited; therefore, identifying new therapeutic …

Gastrointestinal (GI) cancer has a high tumor incidence and mortality rate worldwide.
Despite significant improvements in radiotherapy, chemotherapy, and targeted therapy for GI …