The foundations and development of lipidomics

X Han, RW Gross - Journal of lipid research, 2022 - ASBMB
For over a century, the importance of lipid metabolism in biology was recognized but difficult
to mechanistically understand due to the lack of sensitive and robust technologies for …

Lipidomics: coming to grips with lipid diversity

A Shevchenko, K Simons - Nature reviews Molecular cell biology, 2010 - nature.com
Although lipids are biomolecules with seemingly simple chemical structures, the molecular
composition of the cellular lipidome is complex and, currently, poorly understood. The exact …

Interactive XCMS Online: simplifying advanced metabolomic data processing and subsequent statistical analyses

H Gowda, J Ivanisevic, CH Johnson… - Analytical …, 2014 - ACS Publications
XCMS Online (xcmsonline. scripps. edu) is a cloud-based informatic platform designed to
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …

Novel advances in shotgun lipidomics for biology and medicine

M Wang, C Wang, RH Han, X Han - Progress in lipid research, 2016 - Elsevier
The field of lipidomics, as coined in 2003, has made profound advances and been rapidly
expanded. The mass spectrometry-based strategies of this analytical methodology-oriented …

Multi‐dimensional mass spectrometry‐based shotgun lipidomics and novel strategies for lipidomic analyses

X Han, K Yang, RW Gross - Mass spectrometry reviews, 2012 - Wiley Online Library
Since our last comprehensive review on multi‐dimensional mass spectrometry‐based
shotgun lipidomics (Mass Spectrom. Rev. 24 (2005), 367), many new developments in the …

Advances in mass spectrometry for lipidomics

SJ Blanksby, TW Mitchell - Annual Review of Analytical …, 2010 - annualreviews.org
Recent expansion in research in the field of lipidomics has been driven by the development
of new mass spectrometric tools and protocols for the identification and quantification of …

Cholesterol oxidation products and their biological importance

W Kulig, L Cwiklik, P Jurkiewicz, T Rog… - Chemistry and physics of …, 2016 - Elsevier
The main biological cause of oxysterols is the oxidation of cholesterol. They differ from
cholesterol by the presence of additional polar groups that are typically hydroxyl, keto …

Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry

M Kliman, JC May, JA McLean - … et Biophysica Acta (BBA)-Molecular and …, 2011 - Elsevier
Recent advances in mass spectrometry approaches to the analysis of lipids include the
ability to incorporate both lipid class identification with lipid structural information for …

Cholesterol, sphingolipids, and glycolipids: what do we know about their role in raft-like membranes?

T Róg, I Vattulainen - Chemistry and physics of lipids, 2014 - Elsevier
Lipids rafts are considered to be functional nanoscale membrane domains enriched in
cholesterol and sphingolipids, characteristic in particular of the external leaflet of cell …

Exploring valuable lipids in diatoms

Z Yi, M Xu, X Di, S Brynjolfsson, W Fu - Frontiers in Marine Science, 2017 - frontiersin.org
Diatoms are one major group of algae in oceans that accounts almost half of marine primary
food production and have also been identified as a promising candidate for biofuel …