The protometabolic nature of prebiotic chemistry
N Nogal, M Sanz-Sánchez, S Vela-Gallego… - Chemical Society …, 2023 - pubs.rsc.org
The field of prebiotic chemistry has been dedicated over decades to finding abiotic routes
towards the molecular components of life. There is nowadays a handful of prebiotically …
towards the molecular components of life. There is nowadays a handful of prebiotically …
Minimal RNA self-reproduction discovered from a random pool of oligomers
R Mizuuchi, N Ichihashi - Chemical Science, 2023 - pubs.rsc.org
The emergence of RNA self-reproduction from prebiotic components would have been
crucial in developing a genetic system during the origins of life. However, all known self …
crucial in developing a genetic system during the origins of life. However, all known self …
Trinucleotide building blocks enable exponential ribozyme-catalysed RNA replication and open-ended growth of diverse RNA sequence pools
RNA replication is considered a crucial stage in the origins of life. However, both enzymatic
and non-enzymatic RNA replication cycles are impeded by the “strand separation …
and non-enzymatic RNA replication cycles are impeded by the “strand separation …
A polymerase ribozyme that can synthesize both itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical
event in the origin of life. RNA polymerase ribozymes could constitute such a system, but …
event in the origin of life. RNA polymerase ribozymes could constitute such a system, but …