The relationship between bone marrow adipose tissue and bone metabolism in postmenopausal osteoporosis

J Li, X Chen, L Lu, X Yu - Cytokine & growth factor reviews, 2020 - Elsevier
Postmenopausal osteoporosis (PMOP) is a prevalent skeletal disorder associated with
menopause-related estrogen withdrawal. PMOP is characterized by low bone mass …

Hydroxyapatite use in spine surgery—molecular and clinical aspect

J Litak, W Czyzewski, M Szymoniuk, B Pastuszak… - Materials, 2022 - mdpi.com
Hydroxyapatite possesses desirable properties as a scaffold in tissue engineering: it is
biocompatible at a site of implantation, and it is degradable to non-toxic products. Moreover …

Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1

C Xu, Z Zhang, N Liu, L Li, H Zhong, R Wang… - Nature …, 2022 - nature.com
Ossification of the posterior longitudinal ligament (OPLL) is an emerging spinal disease
caused by heterotopic ossification of the posterior longitudinal ligament. The pathological …

p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner

Q Cong, H Jia, P Li, S Qiu, J Yeh, Y Wang, ZL Zhang… - Scientific reports, 2017 - nature.com
Bone mass is determined by the balance between bone formation, carried out by
mesenchymal stem cell-derived osteoblasts, and bone resorption, carried out by monocyte …

Corylin, a flavonoid derived from Psoralea Fructus, induces osteoblastic differentiation via estrogen and Wnt/β‐catenin signaling pathways

AXD Yu, ML Xu, P Yao, KKL Kwan, YX Liu… - The FASEB …, 2020 - Wiley Online Library
Corylin is a naturally occurring flavonoid isolated from the fruit of Psoralea corylifolia
L.(Fabaceae), which is a Chinese medicinal herb in treating osteoporosis. Although a variety …

Soluble factors on stage to direct mesenchymal stem cells fate

C Sobacchi, E Palagano, A Villa… - … in bioengineering and …, 2017 - frontiersin.org
Mesenchymal stem cells (MSCs) are multipotent stromal cells that are identified by in vitro
plastic adherence, colony-forming capacity, expression of a panel of surface molecules, and …

How to enhance MSCs therapeutic properties? An insight on potentiation methods

CA García-Guerrero, P Fuentes, MJ Araya… - Stem Cell Research & …, 2024 - Springer
Mesenchymal stem/stromal cells (MSCs) have emerged as a promising tool in the field of
regenerative medicine due to their unique therapeutic properties as they can differentiate …

The therapeutic potential of mesenchymal stem cells in treating osteoporosis

T Chen, T Yang, W Zhang, J Shao - Biological research, 2021 - Springer
Osteoporosis (OP), a common systemic metabolic bone disease, is characterized by low
bone mass, increasing bone fragility and a high risk of fracture. At present, the clinical …

Estrogen regulates stemness and senescence of bone marrow stromal cells to prevent osteoporosis via ERβ‐SATB2 pathway

G Wu, R Xu, P Zhang, T Xiao, Y Fu… - Journal of Cellular …, 2018 - Wiley Online Library
Decline of pluripotency in bone marrow stromal cells (BMSCs) associated with estrogen
deficiency leads to a bone formation defect in osteoporosis. Special AT‐rich sequence …

[PDF][PDF] Vibration treatment modulates macrophage polarisation and enhances early inflammatory response in oestrogen-deficient osteoporotic-fracture healing

SK Chow, YN Chim, J Wang, N Zhang, RM Wong… - Eur Cell …, 2019 - ecmjournal.org
Fracture healing is a well-orchestrated and coordinated process and begins with the
inflammatory stage involving the infiltration of immune cells and the release of cytokines …