Capillary electrophoresis (CE) offers fast and high‐resolution separation of charged
analytes from small injection volumes. Coupled to mass spectrometry (MS), it represents a …

Protein glycosylation is one of the most common post-translational modifications that are
essential for cell function across all domains of life. Changes in glycosylation are considered …

Single-cell analysis provides insights into cellular heterogeneity and dynamics of individual
cells. This Feature highlights recent developments in key analytical techniques suited for …

Mass spectrometry (MS)-based top-down proteomics characterizes complex proteomes at
the intact proteoform level and provides an accurate picture of protein isoforms and protein …

Multilevel proteomics aims to delineate proteins at the peptide (bottom‐up proteomics),
proteoform (top‐down proteomics), and protein complex (native proteomics) levels. Capillary …

Capillary electrophoresis-mass spectrometry (CE-MS) is a powerful tool in various fields
including proteomics, metabolomics, and biopharmaceutical and environmental analysis …

In this work, we pioneered the assessment of coupling high-field asymmetric waveform ion
mobility spectrometry (FAIMS) with ultrasensitive capillary electrophoresis hyphenated with …

In this work, we developed an ultra-sensitive CE-MS/MS method for bottom-up proteomics
analysis of limited samples, down to sub-nanogram levels of total protein. Analysis of 880 …

Current developments in single-cell mass spectrometry (MS) aim to deepen proteome
coverage while enhancing analytical speed to study entire cell populations, one cell at a …

Understanding of the relationship between cellular function and molecular composition
holds a key to next-generation therapeutics but requires measurement of all types of …