[HTML][HTML] Current advances in prognostic and diagnostic biomarkers for solid cancers: Detection techniques and future challenges

M Pal, T Muinao, HPD Boruah, N Mahindroo - Biomedicine & …, 2022 - Elsevier
Solid cancers are one of the leading causes of cancer related deaths, characterized by rapid
growth of tumour, and local and distant metastases. Current advances on multimodality care …

Unravelling the role of tumor microenvironment responsive nanobiomaterials in spatiotemporal controlled drug delivery for lung cancer therapy

DA Srinivasarao, S Shah, P Famta… - Drug Delivery and …, 2024 - Springer
Abstract Design and development of efficient drug delivery technologies that impart site-
specificity is the need of the hour for the effective treatment of lung cancer. The emergence …

Targeting Nuclear Receptors in Lung Cancer—Novel Therapeutic Prospects

SK Gangwar, A Kumar, KCH Yap, S Jose, D Parama… - Pharmaceuticals, 2022 - mdpi.com
Lung cancer, the second most commonly diagnosed cancer, is the major cause of fatalities
worldwide for both men and women, with an estimated 2.2 million new incidences and 1.8 …

Thyroid Hormone Receptors as Tumor Suppressors in Cancer

X Zhu, S Cheng - Endocrinology, 2024 - academic.oup.com
Accumulated research has revealed the multifaceted roles of thyroid hormone receptors
(TRs) as potent tumor suppressors across various cancer types. This review explores the …

The Prognostic Significance of TRs in Hepatocellular Carcinoma: Insights from TCGA and GEO Databases

H Zhou, W Wang, R Liang, R Zhu, J Cao… - Biomarker …, 2025 - journals.sagepub.com
Background: Reduced expression of thyroid hormone receptors (TRs) has been observed in
various human malignancies, though its predictive value in hepatocellular carcinoma (HCC) …

Thyroid hormones as biomarkers of lung cancer: a retrospective study

Z Ma, P Song, D Ji, M Zheng, G Qiu, Z Liu… - Annals of …, 2023 - Taylor & Francis
Background Thyroid hormones are key regulators of several physiological processes,
including differentiation, embryonic development, proliferation, and metabolism. Several …

Cytoplasmic localization of Thyroid Hormone Receptor (TR) alpha and nuclear expression of its isoform TRα2 determine survival in breast cancer in opposite ways

M Schneider, MB Köpke, AZ Zehni, T Vilsmaier… - Cancers, 2023 - mdpi.com
Simple Summary There is evidence of a link between breast cancer and thyroid disease.
Patients with thyroid dysfunction have an increased incidence of breast cancer compared to …

[HTML][HTML] Roles of the NR2F Family in the Development, Disease, and Cancer of the Lung

J Yang, W Sun, G Cui - Journal of Developmental Biology, 2024 - mdpi.com
The NR2F family, including NR2F1, NR2F2, and NR2F6, belongs to the nuclear receptor
superfamily. NR2F family members function as transcription factors and play essential roles …

Association between thyroid disorders and extra-thyroidal cancers, a review

X Jia, J Li, Z Jiang - Clinical and Translational Oncology, 2024 - Springer
Thyroid hormone has been shown to have both tumor-promoting and tumor-suppressing
actions, which has led to significant debate over its involvement in the development of …

Reactivated thyroid hormone receptor β attenuates anaplastic thyroid cancer (ATC) stem cell activity

X Zhu, L Zhao, WKL Doolittle… - Endocrine-related …, 2023 - erc.bioscientifica.com
Anaplastic thyroid cancer (ATC) is one of the most aggressive solid cancers in humans, with
limited treatment options. Recent studies suggest that cancer stem cell (CSC) activity …