Glycans, carbohydrate molecules in the realm of biology, are present as biomedically
important glycoconjugates and a characteristic aspect is that their structures in many …

Pathogens including viruses, bacteria, fungi, and parasites continue to shape our lives in
profound ways every day. As we have learned to live in parallel with pathogens, we have …

Shigella, the causative agent of shigellosis, is among the main causes of diarrheal diseases
with still a high morbidity in low-income countries. Relying on chemical synthesis, we …

Glycoconjugates are the ubiquitous components of mammalian cells, mainly synthesized by
covalent bonds of carbohydrates to other biomolecules such as proteins and lipids, with a …

The field of nanomaterials has progressed dramatically over the past decades with important
contributions to the biomedical area. The physicochemical properties of nanomaterials, such …

Sialyl Lewisa (sLea), also known as cancer antigen 19‐9 (CA19‐9), is a tumor‐associated
carbohydrate antigen. The overexpression of sLea on the surface of a variety of cancer cells …

Fluorinated carbohydrates have found many applications in the glycosciences. Typically,
these contain fluorination at a single position. There are not many applications involving …

Simple Summary Alterations in glycosylation are frequently observed in cancer cells.
Different strategies have been proposed to increase drug delivery to the tumor site in order …

Mucin glycoproteins are the major component of mucus and coat epithelial cell surfaces
forming the glycocalyx. The glycocalyx and mucus are involved in the transport of nutrients …

Surface-expressed bacterial polysaccharides are important vaccine antigens but must be
conjugated to a carrier protein for efficient antigen presentation and development of strong …