Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …

Redox balance is essential to maintain the body's normal metabolism. Once disrupted, it
may lead to various chronic diseases, such as diabetes, neurodegenerative diseases …

Background Nuclear factor erythroid 2-related factor 2 (Nrf2) is a classical nuclear
transcription factor that regulates the system's anti-oxidative stress response. The activation …

Alzheimer's disease (AD) is a degenerative disease of the central nervous system that is the
most common type of senile dementia. Ferroptosis is a new type of iron-dependent …

Oxygen metabolism abnormality plays a crucial role in the pathogenesis of Alzheimer's
disease (AD) via several mechanisms, including hypoxia, oxidative stress, and …

Neurodegenerative diseases (NDs) are becoming a serious public health concern as the
world's population continues to age, demanding the discovery of more effective therapies …

Investigations of the effect of antioxidants on idiopathic Parkinson's disease have been
unsuccessful because the preclinical models used to propose these clinical studies do not …

Abstract Heme oxygenase‐1 (HO‐1) is the only way for cells to decompose heme. It can
cleave heme to produce carbon monoxide (CO), ferrous iron (Fe2+), and biliverdin (BV). BV …

Alzheimer's disease (AD) is an irreversible (may be fatal) neurological ailment that affects an
increasing number of elderly people. According to research, AD is the most frequent cause …

The failure of the proper protein turnover in the nervous system is mainly linked to a variety
of neurodegenerative disorders. Therefore, a better understanding of key protein …