Association between abnormal lipid metabolism and tumor

C Li, F Wang, L Cui, S Li, J Zhao, L Liao - Frontiers in Endocrinology, 2023 - frontiersin.org
Metabolic Reprogramming is a sign of tumor, and as one of the three major substances
metabolism, lipid has an obvious impact. Abnormal lipid metabolism is related to the …

The critical impact of sphingolipid metabolism in breast cancer progression and drug response

PA Corsetto, S Zava, AM Rizzo, I Colombo - International Journal of …, 2023 - mdpi.com
Breast cancer is the second leading cause of cancer-related death in women in the world,
and its management includes a combination of surgery, radiation therapy, chemotherapy …

Molecular targets and therapeutic strategies for triple-negative breast cancer

Y Bhat, MR Thrishna, S Banerjee - Molecular Biology Reports, 2023 - Springer
Triple-negative breast cancer (TNBC) is known for its heterogeneous complexity and is often
difficult to treat. TNBC lacks the expression of major hormonal receptors like estrogen …

Unique sphingolipid signature identifies luminal and triple‐negative breast cancer subtypes

A Kar, N Medatwal, K Rajput, S Mandal… - … Journal of Cancer, 2023 - Wiley Online Library
Breast cancer (luminal and triple‐negative breast cancer [TNBC]) is the most common
cancer among women in India and worldwide. Altered sphingolipid levels have emerged as …

Recently reported cell migration inhibitors: Opportunities and challenges for antimetastatic agents

SK Akompong, Y Li, W Gong, L Ye, J Liu - Drug Discovery Today, 2024 - Elsevier
Antimetastatic agents are highly desirable for cancer treatment because of the severe
medical challenges and high mortality resulting from tumor metastasis. Having …

Engineered nanomicelles targeting proliferation and angiogenesis inhibit tumour progression by impairing the synthesis of ceramide-1-phosphate

P Yadav, K Rana, R Chakraborty, A Khan, D Mehta… - Nanoscale, 2024 - pubs.rsc.org
Tumour cells secrete various proangiogenic factors like VEGF, PDGF, and EGF that result in
the formation of highly vascularized tumours with an immunosuppressive tumour …

[HTML][HTML] Identification of SNPs and Candidate Genes Associated with Monocyte/Lymphocyte Ratio and Neutrophil/Lymphocyte Ratio in Duroc × Erhualian F2 …

J Qiao, M Xu, F Xu, Z Che, P Han, X Dai… - International Journal of …, 2024 - mdpi.com
Understanding the pig immune function is crucial for disease-resistant breeding and
potentially for human health research due to shared immune system features. Immune cell …

Sphingomyelin Metabolism Modifies Luminal A Breast Cancer Cell Line under a High Dose of Vitamin C

M Codini, F Fiorani, M Mandarano, S Cataldi… - International Journal of …, 2023 - mdpi.com
The role of sphingomyelin metabolism and vitamin C in cancer has been widely described
with conflicting results ranging from a total absence of effect to possible preventive and/or …

Anti-OAcGD2 antibody in combination with ceramide kinase inhibitor mediates potent antitumor cytotoxicity against breast cancer and diffuse intrinsic pontine glioma …

A Kasprowicz, S Cavdarli, P Delannoy… - Molecular and Cellular …, 2024 - Springer
Abstract O-acetylated GD2 (OAcGD2) is a cancer-related antigen that is currently being
explored for therapeutic use. Exploring the intricate mechanisms behind OAcGD2 synthesis …

[引用][C] Fanning the Flames of Endoplasmic Reticulum (ER) Stress: Can Sphingolipid Metabolism Be Targeted to Enhance ER Stress–Associated Immunogenic Cell …

JA Hengst, AJ Nduwumwami, A Sharma, JK Yun - Molecular Pharmacology, 2024 - ASPET