A Decade of Burkholderia cenocepacia Virulence Determinant Research

SA Loutet, MA Valvano - Infection and immunity, 2010 - Am Soc Microbiol
ABSTRACT The Burkholderia cepacia complex (Bcc) is a group of genetically related
environmental bacteria that can cause chronic opportunistic infections in patients with cystic …

Updates on naringinase: structural and biotechnological aspects

M Puri - Applied microbiology and biotechnology, 2012 - Springer
Naringinases has attracted a great deal of attention in recent years due to its hydrolytic
activities which include the production of rhamnose, and prunin and debittering of citrus fruit …

Biofilm-Grown Burkholderia cepacia Complex Cells Survive Antibiotic Treatment by Avoiding Production of Reactive Oxygen Species

H Van Acker, A Sass, S Bazzini, K De Roy, C Udine… - PLoS one, 2013 - journals.plos.org
The presence of persister cells has been proposed as a factor in biofilm resilience. In the
present study we investigated whether persister cells are present in Burkholderia cepacia …

The Role of Reactive Oxygen Species in Antibiotic-Induced Cell Death in Burkholderia cepacia Complex Bacteria

H Van Acker, J Gielis, M Acke, F Cools, P Cos… - PloS one, 2016 - journals.plos.org
It was recently proposed that bactericidal antibiotics, besides through specific drug-target
interactions, kill bacteria by a common mechanism involving the production of reactive …

A system for the construction of targeted unmarked gene deletions in the genus Burkholderia

RS Flannagan, T Linn… - Environmental …, 2008 - Wiley Online Library
Burkholderia species are extremely multidrug resistant, environmental bacteria with
extraordinary bioremediation and biocontrol properties. At the same time, these bacteria …

Inhibition of Lipopolysaccharide Transport to the Outer Membrane in Pseudomonas aeruginosa by Peptidomimetic Antibiotics

M Werneburg, K Zerbe, M Juhas, L Bigler… - …, 2012 - Wiley Online Library
The asymmetric outer membrane (OM) of Gram‐negative bacteria contains
lipopolysaccharide (LPS) in the outer leaflet and phospholipid in the inner leaflet. During OM …

The Escherichia coli rhaSR-PrhaBAD Inducible Promoter System Allows Tightly Controlled Gene Expression over a Wide Range in Pseudomonas aeruginosa

J Meisner, JB Goldberg - Applied and environmental microbiology, 2016 - Am Soc Microbiol
The araC-ParaBAD inducible promoter system is tightly controlled and allows gene
expression to be modulated over a wide range in Escherichia coli, which has led to its …

A Putative Gene Cluster for Aminoarabinose Biosynthesis Is Essential for Burkholderia cenocepacia Viability

XP Ortega, ST Cardona, AR Brown… - Journal of …, 2007 - Am Soc Microbiol
Using a conditional mutagenesis strategy we demonstrate here that a gene cluster encoding
putative aminoarabinose (Ara4N) biosynthesis enzymes is essential for the viability of …

Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS

YC Wong, M Abd El Ghany, R Naeem, KW Lee… - Frontiers in …, 2016 - frontiersin.org
Burkholderia cenocepacia infection often leads to fatal cepacia syndrome in cystic fibrosis
patients. However, antibiotic therapy rarely results in complete eradication of the pathogen …

Bacterial sugar utilization gives rise to distinct single‐cell behaviours

T Afroz, K Biliouris, Y Kaznessis… - Molecular …, 2014 - Wiley Online Library
Inducible utilization pathways reflect widespread microbial strategies to uptake and
consume sugars from the environment. Despite their broad importance and extensive …