Inflammation and the pathogenesis of atrial fibrillation

YF Hu, YJ Chen, YJ Lin, SA Chen - Nature Reviews Cardiology, 2015 - nature.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia. However, the development of
preventative therapies for AF has been disappointing. The infiltration of immune cells and …

Role of inflammation in atrial fibrillation pathophysiology and management

M Harada, DR Van Wagoner, S Nattel - Circulation journal, 2015 - jstage.jst.go.jp
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia, but the methods
available for treating AF and its complications (of which the most important is …

Atrial myopathy

MJ Shen, R Arora, J Jalife - JACC: Basic to Translational Science, 2019 - jacc.org
This paper discusses the evolving concept of atrial myopathy by presenting how it develops
and how it affects the properties of the atria. It also reviews the complex relationships among …

Inflammation in atrial fibrillation

Y Guo, GYH Lip, S Apostolakis - Journal of the American College of …, 2012 - jacc.org
Atrial fibrillation (AF) is associated with increased risk for stroke and systemic embolism.
There is plausible evidence linking inflammation to the initiation and perpetuation of AF and …

The role of nitric oxide on endothelial function

D Tousoulis, AM Kampoli… - Current vascular …, 2012 - ingentaconnect.com
The vascular endothelium is a monolayer of cells between the vessel lumen and the
vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized …

OSA and cardiac arrhythmogenesis: mechanistic insights

AM May, DR Van Wagoner, R Mehra - Chest, 2017 - Elsevier
A surge of data has reproducibly identified strong associations of OSA with cardiac
arrhythmias. As an extension of epidemiologic and clinic-based findings, experimental …

Flavonoids in atherosclerosis: an overview of their mechanisms of action

G Siasos, D Tousoulis, V Tsigkou… - Current Medicinal …, 2013 - ingentaconnect.com
Polyphenols are composed of a wide variety of molecules that are classified into several
categories, according to their chemical type such as phenolic acids, flavonoids, stilbenes …

[HTML][HTML] Mechanisms of oxidative stress in human aortic aneurysms—association with clinical risk factors for atherosclerosis and disease severity

B Guzik, A Sagan, D Ludew, W Mrowiecki… - International journal of …, 2013 - Elsevier
Aortic abdominal aneurysms (AAA) are important causes of cardiovascular morbidity and
mortality. Oxidative stress may link multiple mechanisms of AAA including vascular …

NADPH oxidases and oxidative stress in the pathogenesis of atrial fibrillation

R Ramos-Mondragón, A Lozhkin, AE Vendrov… - Antioxidants, 2023 - mdpi.com
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and its prevalence
increases with age. The irregular and rapid contraction of the atria can lead to ineffective …

Associations of dietary and lifestyle components with atrial fibrillation

K Leszto, W Frąk, S Kurciński, J Sinkowska, S Skwira… - Nutrients, 2024 - mdpi.com
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia that still remains a significant health
concern, especially due to its consequences, including stroke and heart failure. This review …