The role of the gut microbiome in cattle production and health: driver or passenger?

E O'Hara, ALA Neves, Y Song… - Annual review of animal …, 2020 - annualreviews.org
Ruminant production systems face significant challenges currently, driven by heightened
awareness of their negative environmental impact and the rapidly rising global population …

[HTML][HTML] Unsupervised multi-omics data integration methods: a comprehensive review

N Vahabi, G Michailidis - Frontiers in genetics, 2022 - frontiersin.org
Through the developments of Omics technologies and dissemination of large-scale
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …

[HTML][HTML] mixOmics: An R package for 'omics feature selection and multiple data integration

F Rohart, B Gautier, A Singh… - PLoS computational …, 2017 - journals.plos.org
The advent of high throughput technologies has led to a wealth of publicly available 'omics
data coming from different sources, such as transcriptomics, proteomics, metabolomics …

[HTML][HTML] Integrated omics: tools, advances and future approaches

BB Misra, C Langefeld, M Olivier… - Journal of molecular …, 2019 - jme.bioscientifica.com
With the rapid adoption of high-throughput omic approaches to analyze biological samples
such as genomics, transcriptomics, proteomics, and metabolomics, each analysis can …

[HTML][HTML] Methods for the integration of multi-omics data: mathematical aspects

M Bersanelli, E Mosca, D Remondini, E Giampieri… - BMC …, 2016 - Springer
Background Methods for the integrative analysis of multi-omics data are required to draw a
more complete and accurate picture of the dynamics of molecular systems. The complexity …

[HTML][HTML] Evaluation and comparison of multi-omics data integration methods for cancer subtyping

R Duan, L Gao, Y Gao, Y Hu, H Xu… - PLoS computational …, 2021 - journals.plos.org
Computational integrative analysis has become a significant approach in the data-driven
exploration of biological problems. Many integration methods for cancer subtyping have …

In Vitro Human Cell Line Models to Predict Clinical Response to Anticancer Drugs

N Niu, L Wang - Pharmacogenomics, 2015 - Taylor & Francis
In vitro human cell line models have been widely used for cancer pharmacogenomic studies
to predict clinical response, to help generate pharmacogenomic hypothesis for further …

Multi-omics integration—a comparison of unsupervised clustering methodologies

G Tini, L Marchetti, C Priami… - Briefings in …, 2019 - academic.oup.com
With the recent developments in the field of multi-omics integration, the interest in factors
such as data preprocessing, choice of the integration method and the number of different …

Epigenetic regulation of gene expression in cancer: techniques, resources and analysis

LT Kagohara, GL Stein-O'Brien, D Kelley… - Briefings in …, 2018 - academic.oup.com
Cancer is a complex disease, driven by aberrant activity in numerous signaling pathways in
even individual malignant cells. Epigenetic changes are critical mediators of these functional …

[HTML][HTML] Classifying breast cancer subtypes on multi-omics data via sparse canonical correlation analysis and deep learning

Y Huang, P Zeng, C Zhong - BMC bioinformatics, 2024 - Springer
Background Classifying breast cancer subtypes is crucial for clinical diagnosis and
treatment. However, the early symptoms of breast cancer may not be apparent. Rapid …