Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

COVID-19 and obesity in childhood and adolescence: a clinical review

CA Nogueira-de-Almeida, LA Del Ciampo… - Jornal de …, 2020 - SciELO Brasil
Objective: To identify factors that contribute to the increased susceptibility and severity of
COVID-19 in obese children and adolescents, and its health consequences. Sources …

SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages

GJ Martínez-Colón, K Ratnasiri, H Chen… - Science Translational …, 2022 - science.org
Obesity, characterized by chronic low-grade inflammation of the adipose tissue, is
associated with adverse coronavirus disease 2019 (COVID-19) outcomes, yet the …

On the whereabouts of SARS-CoV-2 in the human body: A systematic review

W Trypsteen, J Van Cleemput, W Snippenberg… - PLoS …, 2020 - journals.plos.org
Since SARS-CoV-2 appeared in the human population, the scientific community has
scrambled to gather as much information as possible to find good strategies for the …

Obesity and infectious diseases: pathophysiology and epidemiology of a double pandemic condition

G Pugliese, A Liccardi, C Graziadio, L Barrea… - International Journal of …, 2022 - nature.com
The current pandemic due to widespread SARS-CoV-19 infection has again highlighted the
role of obesity, whose global prevalence increased up to 13%, as a risk factor for both …

Novel systemic inflammation markers to predict COVID-19 prognosis

A Karimi, P Shobeiri, A Kulasinghe… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) has resulted in a global pandemic, challenging both
the medical and scientific community for the development of novel vaccines and a greater …

Obesity as a risk factor for severe COVID-19 and complications: a review

F Demeulemeester, K de Punder, M van Heijningen… - Cells, 2021 - mdpi.com
Emerging data suggest that obesity is a major risk factor for the progression of major
complications such as acute respiratory distress syndrome (ARDS), cytokine storm and …

The triumvirate: why hypertension, obesity, and diabetes are risk factors for adverse effects in patients with COVID-19

H Shah, MSH Khan, NV Dhurandhar, V Hegde - Acta diabetologica, 2021 - Springer
The outbreak of coronavirus disease 2019 (COVID-19) caused by a novel coronavirus,
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a pandemic …

Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral–bacterial interactions

IL Kruglikov, M Shah, PE Scherer - Elife, 2020 - elifesciences.org
Obesity and diabetes are established comorbidities for COVID-19. Adipose tissue
demonstrates high expression of ACE2 which SARS-CoV-2 exploits to enter host cells. This …

COVID-19 in joint ageing and osteoarthritis: current status and perspectives

M Lauwers, M Au, S Yuan, C Wen - International journal of molecular …, 2022 - mdpi.com
COVID-19 is a trending topic worldwide due to its immense impact on society. Recent trends
have shifted from acute effects towards the long-term morbidity of COVID-19. In this review …