Background—Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …

Flaws in the design of randomized trials may bias intervention effect estimates and increase
between-trial heterogeneity. Empirical evidence suggests that these problems are greatest …

Summary 23% of the total global burden of disease is attributable to disorders in people
aged 60 years and older. Although the proportion of the burden arising from older people (≥ …

The WHO World report on ageing and health is not for the book shelf it is a living breathing
testament to all older people who have fought for their voice to be heard at all levels of …

Worldwide, populations are rapidly ageing. This demographic shift presents both
opportunities and challenges. Most people aspire to live a long and healthy life, and older …

Apart from its main function in the mitochondria as a key element in electron transport,
Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant …

Importance Hypertension is a major risk factor for cardiovascular disease and can be
modified through lifestyle and pharmacological interventions to reduce cardiovascular …

Importance The effect of serious injuries, such as hip fracture and head injury, on mortality
and function is comparable to that of cardiovascular events. Concerns have been raised …

The 2017 update of The Canadian Stroke Best Practice Recommendations for the
Secondary Prevention of Stroke is a collection of current evidence-based recommendations …

Background This is the first update of a review published in 2009. Sustained moderate to
severe elevations in resting blood pressure leads to a critically important clinical question …