Antiviral peptides as promising therapeutic drugs

LCP Vilas Boas, ML Campos, RLA Berlanda… - Cellular and Molecular …, 2019 - Springer
While scientific advances have led to large-scale production and widespread distribution of
vaccines and antiviral drugs, viruses still remain a major cause of human diseases today …

Herpes simplex virus cell entry mechanisms: an update

K Madavaraju, R Koganti, I Volety… - Frontiers in cellular …, 2021 - frontiersin.org
Herpes simplex virus (HSV) can infect a broad host range and cause mild to life threating
infections in humans. The surface glycoproteins of HSV are evolutionarily conserved and …

Cell entry mechanisms of HSV: what we have learned in recent years

AM Agelidis, D Shukla - Future virology, 2015 - Taylor & Francis
HSV type-1 and-2 are widespread pathogens producing lifelong infection with multiple
sequelae, including oral, ocular and genital disease. The process of herpesvirus entry is a …

Discovering small-molecule therapeutics against SARS-CoV-2

V Tiwari, JC Beer, NV Sankaranarayanan… - Drug Discovery …, 2020 - Elsevier
Highlights•SARS-CoV-2's high homology with SARS-CoV did not prove beneficial
immediately.•Targeting viral attachment and fusion proteins has yielded good early …

Virostatic potential of micro–nano filopodia-like ZnO structures against herpes simplex virus-1

YK Mishra, R Adelung, C Röhl, D Shukla, F Spors… - Antiviral research, 2011 - Elsevier
Herpes simplex virus type-1 (HSV-1) entry into target cell is initiated by the ionic interactions
between positively charged viral envelop glycoproteins and a negatively charged cell …

Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptor

CW Tan, CL Poh, IC Sam, YF Chan - Journal of virology, 2013 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV-71) infections are usually associated with mild hand, foot,
and mouth disease in young children but have been reported to cause severe neurological …

Applications of the phage display technology in molecular biology, biotechnology and medicine

K Pierzynowska, J Morcinek-Orłowska… - Critical Reviews in …, 2024 - Taylor & Francis
The phage display technology is based on the presentation of peptide sequences on the
surface of virions of bacteriophages. Its development led to creation of sophisticated systems …

Herpes simplex virus infects most cell types in vitro: clues to its success

GA Karasneh, D Shukla - Virology journal, 2011 - Springer
Herpes simplex virus (HSV) type-1 and type-2 have evolved numerous strategies to infect a
wide range of hosts and cell types. The result is a very successful prevalence of the virus in …

Nanostructures for the inhibition of viral infections

S Szunerits, A Barras, M Khanal, Q Pagneux… - Molecules, 2015 - mdpi.com
Multivalent interactions are omnipresent in biology and confer biological systems with
dramatically enhanced affinities towards different receptors. Such multivalent binding …

Pathological processes activated by herpes simplex virus-1 (HSV-1) infection in the cornea

L Koujah, RK Suryawanshi, D Shukla - Cellular and molecular life …, 2019 - Springer
Herpes simplex virus type-1 (HSV-1) is a ubiquitous pathogen that infects a large majority of
the human population worldwide. It is also a leading cause of infection-related blindness in …