Ultrafast processes in light-absorbing proteins have been implicated in the primary step in
the light-to-energy conversion and the initialization of photoresponsive biological functions …

The incredible potential for fluorescent proteins to revolutionize biology has inspired the
development of a variety of design strategies to address an equally broad range of …

UV-absorbing rhodopsins are essential for UV vision and sensing in all kingdoms of life.
Unlike the well-known visible-absorbing rhodopsins, which bind a protonated retinal Schiff …

A novel atomistic methodology to perform free energy geometry optimization of a retinal
chromophore covalently bound to any rhodopsin-like protein cavity is presented and …

Abstract FR‐1V, a fluorene‐based aldehydic chromophore, binds its target protein as an
imine to yield a highly bathochromic pigment, CF‐2, a prototypic protein–dye tagging system …

Carotenoids are usually only weakly fluorescent despite being very strong absorbers in the
mid-visible region because their first two excited singlet states, S1 and S2, have very short …

In humans, vision is limited to a small fraction of the whole electromagnetic spectrum. One
possible strategy for enhancing vision in deep-red or poor-light conditions consists of …

The use of light‐responsive proteins to control both living or synthetic cells, is at the core of
the expanding fields of optogenetics and synthetic biology. It is thus apparent that a richer …

Microbial rhodopsin, a pivotal photoreceptor protein, has garnered widespread application
in diverse fields such as optogenetics, biotechnology, biodevices, etc. However, current …

Cysteine-based Michael addition is a widely employed strategy for covalent conjugation of
proteins, peptides, and drugs. The covalent reaction is irreversible in most cases, leading to …