Ubiquitin is the founding member of a family of structurally conserved proteins that regulate
a host of processes in eukaryotic cells. Ubiquitin and its relatives carry out their functions …

▪ Abstract Sorting of transmembrane proteins to endosomes and lysosomes is mediated by
signals present within the cytosolic domains of the proteins. Most signals consist of short …

Grain weight is one of the most important components of grain yield and is controlled by
quantitative trait loci (QTLs) derived from natural variations in crops. However, the molecular …

Interest in MHC-E–restricted CD8+ T cell responses has been aroused by the discovery of
their efficacy in controlling simian immunodeficiency virus (SIV) infection in a vaccine model …

Presumably because of the selective pressure exerted by the immune system, many viruses
have evolved proteins that interfere with antigen presentation by major histocompatibility …

▪ Abstract Ubiquitin regulates protein transport between membrane compartments by serving
as a sorting signal on protein cargo and by controlling the activity of trafficking machinery …

Withdrawal of nutrients triggers an exit from the cell division cycle, the induction of
autophagy, and eventually the activation of cell death pathways. The relation, if any, among …

Abstract Approximately 5% of the Arabidopsis (Arabidopsis thaliana) proteome is predicted
to be involved in the ubiquitination/26S proteasome pathway. The majority of these …

The ESCRT machinery consists of the peripheral membrane protein complexes ESCRT-0,-I,-
II,-III, and Vps4–Vta1, and the ALIX homodimer. The ESCRT system is required for …

The cell surface display of peptides by MHC class I molecules to lymphocytes provides the
host with an important surveillance mechanism to protect against invading pathogens …