A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence

D Balasubramanian, L Schneper, H Kumari… - Nucleic acids …, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia

JR Govan, V Deretic - Microbiological reviews, 1996 - Am Soc Microbiol
Respiratory infections with Pseudomonas aeruginosa and Burkholderia cepacia play a
major role in the pathogenesis of cystic fibrosis (CF). This review summarizes the latest …

[HTML][HTML] Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist

JB Lyczak, CL Cannon, GB Pier - Microbes and infection, 2000 - Elsevier
Pseudomonas aeruginosa is an ubiquitous pathogen capable of infecting virtually all
tissues. A large variety of virulence factors contribute to its importance in burn wounds, lung …

Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients.

DW Martin, MJ Schurr, MH Mudd… - Proceedings of the …, 1993 - National Acad Sciences
Chronic respiratory infections with mucoid Pseudomonas aeruginosa are the leading cause
of high mortality and morbidity in cystic fibrosis (CF). The initially colonizing strains are …

Role of Alginate and Its O Acetylation in Formation of Pseudomonas aeruginosa Microcolonies and Biofilms

DE Nivens, DE Ohman, J Williams… - Journal of …, 2001 - Am Soc Microbiol
Attenuated total reflection/Fourier transform-infrared spectrometry (ATR/FT-IR) and scanning
confocal laser microscopy (SCLM) were used to study the role of alginate and alginate …

Identification of psl, a Locus Encoding a Potential Exopolysaccharide That Is Essential for Pseudomonas aeruginosa PAO1 Biofilm Formation

KD Jackson, M Starkey, S Kremer, MR Parsek… - 2004 - Am Soc Microbiol
Bacteria inhabiting biofilms usually produce one or more polysaccharides that provide a
hydrated scaffolding to stabilize and reinforce the structure of the biofilm, mediate cell-cell …

Understanding the control of Pseudomonas aeruginosa alginate synthesis and the prospects for management of chronic infections in cystic fibrosis

DM Ramsey, DJ Wozniak - Molecular microbiology, 2005 - Wiley Online Library
Decades of research have been dedicated to the study of the opportunistic pathogen
Pseudomonas aeruginosa, a Gram‐negative, environmental bacterium that secretes the …

Biomolecular Mechanisms of Pseudomonas aeruginosa and Escherichia coli Biofilm Formation

G Laverty, SP Gorman, BF Gilmore - Pathogens, 2014 - mdpi.com
Pseudomonas aeruginosa and Escherichia coli are the most prevalent Gram-negative
biofilm forming medical device associated pathogens, particularly with respect to catheter …

Periplasmic stress and ECF sigma factors

TL Raivio, TJ Silhavy - Annual Reviews in Microbiology, 2001 - annualreviews.org
▪ Abstract Envelope stress responses play important pysiological roles in a variety of
processes, including protein folding, cell wall biosynthesis, and pathogenesis. Many of these …

The anti-sigma factors

KT Hughes, K Mathee - Annual review of microbiology, 1998 - annualreviews.org
▪ Abstract A mechanism for regulating gene expression at the level of transcription utilizes an
antagonist of the sigma transcription factor known as the anti-sigma (anti-σ) factor. The …