Exploring the landscape of Babesia bovis vaccines: progress, challenges, and opportunities

JHM Santos, HV Siddle, A Raza, DI Stanisic… - Parasites & …, 2023 - Springer
Bovine babesiosis, caused by different Babesia spp. such as B. bovis, B. bigemina, B.
divergens, and B. major, is a global disease that poses a serious threat to livestock …

Advances in Babesia Vaccine Development: An Overview

M Jerzak, A Gandurski, M Tokaj, W Stachera, M Szuba… - Pathogens, 2023 - mdpi.com
Babesiosis is a tick-borne zoonotic disease, which is caused by various species of
intracellular Babesia parasite. It is a problem not only for the livestock industry but also for …

Molecular characterization and genetic diversity of Babesia bovis and Babesia bigemina of cattle in Thailand

N Srionrod, P Nooroong, N Poolsawat… - Frontiers in Cellular …, 2022 - frontiersin.org
Babesia bovis and B. bigemina are the most common tick-borne parasites that cause bovine
babesiosis which effects livestock production, leading to economic losses in tropical and …

Preliminary evaluation of the protective effects of recombinant AMA1 and IMP1 against Eimeria stiedae infection in rabbits

J Xiao, R Zheng, X Bai, J Pu, H Chen, X Gu, Y Xie… - Parasites & vectors, 2022 - Springer
Background Eimeria stiedae parasitizes the bile duct, causing hepatic coccidiosis in rabbits.
Coccidiosis control using anticoccidials led to drug resistance and residues; therefore …

Babesia gibsoni Whole-Genome Sequencing, Assembling, Annotation, and Comparative Analysis

Q Liu, XA Guan, DF Li, YX Zheng, S Wang… - Microbiology …, 2023 - Am Soc Microbiol
The intracellular protozoan parasite Babesia gibsoni infects canine erythrocytes and causes
babesiosis. The hazards to animal health have increased due to the rise of B. gibsoni …

Genetic Diversity of Merozoite Surface Antigens in Global Babesia bovis Populations

ES El-Alfy, I Abbas, R Elseadawy, SAES El-Sayed… - Genes, 2023 - mdpi.com
Cattle can be severely infected with the tick-borne protozoa Babesia bovis, giving rise to
serious economic losses. Invasion of the host's RBCs by the parasite merozoite/sporozoites …

Evaluation of the humoral and mucosal immune response of a multiepitope vaccine against COVID-19 in pigs

J Mosqueda, DJ Hernandez-Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction This study evaluated the immune response to a multiepitope recombinant
chimeric protein (CHIVAX) containing B-and T-cell epitopes of the SARS-CoV-2 spike's …

Spherical Body Protein 4 from Babesia bigemina: A Novel Gene That Contains Conserved B-Cell Epitopes and Induces Cross-Reactive Neutralizing Antibodies in …

J Mosqueda, DJ Hernandez-Silva, MW Ueti… - Pathogens, 2023 - mdpi.com
Bovine babesiosis is a tick-transmitted disease caused by intraerythrocytic protozoan
parasites of the genus Babesia. Its main causative agents in the Americas are Babesia …

A conserved motif in the immune-subdominant RAP-1 related antigen of Babesia bovis contains a B-cell epitope recognized by antibodies from protected cattle

MJ Rojas, RG Bastos, J Navas, JM Laughery… - Frontiers in …, 2024 - frontiersin.org
Introduction Babesia bovis, a tick-borne apicomplexan parasite causing bovine babesiosis,
remains a significant threat worldwide, and improved and practical vaccines are needed …

Developing Anti-Babesia bovis Blood Stage Vaccines: A New Perspective Regarding Synthetic Vaccines

L Cuy-Chaparro, C Reyes, EV Díaz-Guiot… - International Journal of …, 2023 - mdpi.com
Bovine babesiosis is caused by the Apicomplexa parasites from the genus Babesia. It is one
of the most important tick-borne veterinary diseases worldwide; Babesia bovis being the …