A systematic review of polycyclic aromatic hydrocarbon derivatives: occurrences, levels, biotransformation, exposure biomarkers, and toxicity

B Peng, Q Dong, F Li, T Wang, X Qiu… - Environmental Science & …, 2023 - ACS Publications
Polycyclic aromatic hydrocarbon (PAH) derivatives constitute a significant class of emerging
contaminants that have been ubiquitously detected in diverse environmental matrixes, with …

Oxygenated polycyclic aromatic hydrocarbons in food: Toxicity, occurrence and potential sources

X Ma, S Wu - Critical reviews in food science and nutrition, 2024 - Taylor & Francis
Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are polycyclic aromatic
hydrocarbons (PAHs) functionalized with at least one carbonyl group and are generally …

Nontarget screening of novel urinary biomarkers for occupational exposure to toxic chemicals from coking industry using HPLC-QTOF-MS

H Li, S Zhang, C Yao, R He, P Lu, G Li… - Environmental …, 2023 - ACS Publications
High-resolution mass spectrometry is an advanced technique for comprehensive screening
of toxic chemicals. In this study, urine samples were collected from both an occupationally …

[HTML][HTML] The key characteristics of cardiotoxicity for the pervasive pollutant phenanthrene

E England, JW Morris, C Bussy, JC Hancox… - Journal of Hazardous …, 2024 - Elsevier
The key characteristic (KCs) framework has been used previously to assess the
carcinogenicity and cardiotoxicity of various chemical and pharmacological agents. Here …

The levels of polycyclic aromatic hydrocarbons and their derivatives in plasma and their effect on mitochondrial DNA methylation in the oilfield workers

Y Jia, W Li, Y Li, L Zhao, C Li, L Wang, J Fang, S Song… - Toxics, 2023 - mdpi.com
This study focuses on the components and levels of polycyclic aromatic hydrocarbons
(PAHs) and their derivatives (MPAHs and OPAHs) in plasma samples from 19 oil workers …

Enrichment of polycyclic aromatic hydrocarbon metabolizing microorganisms on the oral mucosa of tobacco users

L Tao, MP Chiarelli, S Pavlova, A Kolokythas… - PeerJ, 2024 - peerj.com
Certain soil microbes resist and metabolize polycyclic aromatic hydrocarbons (PAHs). The
same is true for a subset of skin microbes. In the human mouth, oral microbes have the …

Activity-Based Protein Profiling to Probe Relationships between Cytochrome P450 Enzymes and Early-Age Metabolism of Two Polycyclic Aromatic Hydrocarbons …

KA Gaither, WL Garcia, KJ Tyrrell… - Chemical Research …, 2024 - ACS Publications
A growing body of literature has linked early-life exposures to polycyclic aromatic
hydrocarbons (PAH) with adverse neurodevelopmental effects. Once in the body …

Polychlorinated biphenyl quinone metabolite promotes p53-dependent DNA damage checkpoint activation, S-phase cycle arrest and extrinsic apoptosis in human …

X Song, L Li, Q Shi, HJ Lehmler, J Fu… - Chemical research in …, 2015 - ACS Publications
Polychlorinated biphenyls (PCBs) are a group of persistent organic pollutants. The toxic
behavior and mechanism of PCBs individuals and congeners have been extensively …

Atropselective partitioning of polychlorinated biphenyls in a HepG2 cell culture system: experimental and modeling results

CY Zhang, S Flor, G Ludewig… - Environmental science & …, 2020 - ACS Publications
Cell culture models are used to study the toxicity of polychlorinated biphenyls (PCBs);
however, it is typically unknown how much PCB enters the cells and, for chiral PCBs, if the …

Copper(0)/Selectfluor System-Promoted Oxidative Carbon–Carbon Bond Cleavage/Annulation of o-Aryl Chalcones: An Unexpected Synthesis of 9,10 …

H Bao, Z Xu, D Wu, H Zhang, H Jin… - The Journal of Organic …, 2017 - ACS Publications
A general and efficient protocol for the synthesis of 9, 10-phenanthraquinone derivatives has
been successfully developed involving a copper (0)/Selectfluor system-promoted oxidative …