HPV post-infection microenvironment and cervical cancer

Y Yuan, X Cai, F Shen, F Ma - Cancer Letters, 2021 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted virus worldwide.
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …

[HTML][HTML] The molecular and cellular origin of human prostate cancer

JR Packer, NJ Maitland - Biochimica et Biophysica Acta (BBA)-Molecular …, 2016 - Elsevier
Prostate cancer is the most commonly diagnosed male malignancy. Despite compelling
epidemiology, there are no definitive aetiological clues linking development to frequency …

Papillomavirus E5: the smallest oncoprotein with many functions

A Venuti, F Paolini, L Nasir, A Corteggio, S Roperto… - Molecular cancer, 2011 - Springer
Papillomaviruses (PVs) are established agents of human and animal cancers. They infect
cutaneous and mucous epithelia. High Risk (HR) Human PVs (HPVs) are consistently …

Immune evasion in human papillomavirus-associated cervical cancer

RW Tindle - Nature Reviews Cancer, 2002 - nature.com
Tumour-associated viruses produce antigens that, on the face of it, are ideal targets for
immunotherapy. Unfortunately, these viruses are experts at avoiding or subverting the host …

Mechanisms used by human papillomaviruses to escape the host immune response

S Kanodia, LM Fahey, WM Kast - Current cancer drug targets, 2007 - ingentaconnect.com
The greatest risk factor for the development of cervical and other cancers that have been
linked to the human papillomavirus (HPV) family is the persistence of the virus. To persist for …

Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions

T Garcia-Iglesias, A del Toro-Arreola… - BMC cancer, 2009 - Springer
Background Persistent high risk HPV infection can lead to cervical cancer, the second most
common malignant tumor in women worldwide. NK cells play a crucial role against tumors …

[HTML][HTML] Interaction of human papillomaviruses with the host immune system: a well evolved relationship

IH Frazer - Virology, 2009 - Elsevier
Human papillomavirus (HPV) infections are generally long lasting, and a host immune
response to infection is hard to detect. Nevertheless immunocompromised subjects control …

E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I

GH Ashrafi, MR Haghshenas… - … journal of cancer, 2005 - Wiley Online Library
Papillomaviruses have evolved mechanisms that result in escape from host immune
surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers …

Warts and all: human papillomavirus in primary immunodeficiencies

JW Leiding, SM Holland - Journal of allergy and clinical immunology, 2012 - Elsevier
Infection with human papillomavirus (HPV) is almost universal and eventually asymptomatic,
but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an …

Human papillomavirus and oropharynx cancer: biology, detection and clinical implications

CT Allen, JS Lewis Jr, SK El‐Mofty… - The …, 2010 - Wiley Online Library
Objectives: To review evidence for the role of human papillomavirus (HPV) in the etiology of
oropharyngeal cancers, methods of viral detection, and the resulting clinical implications …