Immunogenic cell death, DAMPs and prothymosin α as a putative anticancer immune response biomarker

AI Birmpilis, A Paschalis, A Mourkakis, P Christodoulou… - Cells, 2022 - mdpi.com
The new and increasingly studied concept of immunogenic cell death (ICD) revealed a
previously unknown perspective of the various regulated cell death (RCD) modalities …

Prothymosin alpha: an alarmin and more...

P Samara, CE Karachaliou, K Ioannou… - Current Medicinal …, 2017 - ingentaconnect.com
Background/Objective: Prothymosin alpha (proTα) is a ubiquitous polypeptide first isolated
by Haritos in 1984, whose role still remains partly elusive. We know that proTα acts both …

Precursors of thymic peptides as stress sensors

S Lunin, M Khrenov, O Glushkova… - Expert opinion on …, 2020 - Taylor & Francis
Introduction A large volume of data indicates that the known thymic hormones, thymulin,
thymopoietin, thymosin-α, thymosin-β, and thymic humoral factor-y2, exhibit different spectra …

Antitumor reactive T-cell responses are enhanced in vivo by DAMP prothymosin alpha and its C-terminal decapeptide

AI Birmpilis, CE Karachaliou, P Samara, K Ioannou… - Cancers, 2019 - mdpi.com
Prothymosin α (proTα) and its C-terminal decapeptide proTα (100–109) were shown to
pleiotropically enhance innate and adaptive immune responses. Their activities have been …

68Ga-WRWWWW Is a Potential Positron Emission Tomography Probe for Imaging Inflammatory Diseases by Targeting Formyl Peptide Receptor 2

X Pan, J Zhu, Z Xu, Q Xiao, X Zhou, K Xu… - Molecular …, 2022 - ACS Publications
Inflammation plays a significant role in many physiological and pathological processes.
Molecular imaging could provide functional as well as anatomical information for visualizing …