NKG2D is an activating receptor expressed on the surface of natural killer (NK) cells, CD8+
T cells, and subsets of CD4+ T cells, invariant NKT cells (iNKT), and γδ T cells. In humans …

Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

A systematic quantitative analysis of temporal changes in host and viral proteins throughout
the course of a productive infection could provide dynamic insights into virus-host …

Human cytomegalovirus (HCMV) infection induces both innate immune responses including
Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ …

The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

Human cytomegalovirus is a widespread pathogen of major medical importance. It causes
significant morbidity and mortality in immunocompromised individuals, and congenital …

The activating natural killer group 2 member D (NKG 2 D) receptor is expressed on NK cells,
cytotoxic T cells and additional T cell subsets. Ligands for human NKG 2 D comprise two …

Major mechanisms for the recognition of pathogens by immune cells have evolved to
employ classical and non-classical major histocompatibility complex class I (MHC I) …

Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to
the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes …

The recent approval of letermovir marks a new era of therapy for human cytomegalovirus
(HCMV) infections, particularly for the prevention of HCMV disease in hematopoietic stem …