STAT3 and its targeting inhibitors in oral squamous cell carcinoma
M Jiang, B Li - Cells, 2022 - mdpi.com
Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of
oral mucosa and accounts for approximately 90% of oral cancers. Current therapeutic …
oral mucosa and accounts for approximately 90% of oral cancers. Current therapeutic …
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas
Oral squamous cell carcinomas (OSCC) and esophageal squamous cell carcinomas
(ESCC) exhibit a survival rate of less than 60% and 40%, respectively. Late‐stage diagnosis …
(ESCC) exhibit a survival rate of less than 60% and 40%, respectively. Late‐stage diagnosis …
The multifaceted role of STAT3 pathway and its implication as a potential therapeutic target in oral cancer
Oral cancer is one of the leading causes of cancer-related deaths, and it has become a
matter of serious concern due to the alarming rise in its incidence rate worldwide. Despite …
matter of serious concern due to the alarming rise in its incidence rate worldwide. Despite …
[HTML][HTML] miR-182-5p promotes growth in oral squamous cell carcinoma by inhibiting CAMK2N1
N Li, CC Nan, XY Zhong, JQ Weng, HD Fan… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Emerging evidence suggests that the propagation of oral squamous cell
carcinoma (OSCC) is influenced by the abnormal expression of microRNAs (miRNAs). This …
carcinoma (OSCC) is influenced by the abnormal expression of microRNAs (miRNAs). This …
Discovery of EMD37, a 1, 2, 4-oxadiazole derivative, as a novel endoplasmic reticulum stress inducer with potent anticancer activity
Targeting endoplasmic reticulum (ER) stress presents a promising strategy in cancer
therapy. We previously reported a series of 1, 2, 4-oxadiazole derivatives that induced the …
therapy. We previously reported a series of 1, 2, 4-oxadiazole derivatives that induced the …
[HTML][HTML] Lipopolysaccharide promoted proliferation and adipogenesis of preadipocytes through JAK/STAT and AMPK-regulated cPLA2 expression
CC Chang, KC Sia, JF Chang, CM Lin… - … Journal of Medical …, 2019 - ncbi.nlm.nih.gov
The proliferation and adipogenesis of preadipocytes played important roles in the
development of adipose tissue and contributed much to the processes of obesity. On the …
development of adipose tissue and contributed much to the processes of obesity. On the …
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro …
C Pan, H Qin, H Jin, W Chen, H Guo, X Han - Toxicology, 2022 - Elsevier
To date, no reported studies have explored the impacts of microcystin-LR (MC-LR) on
bladder tissues, and even the occurrence of bladder cancer. The current study explores the …
bladder tissues, and even the occurrence of bladder cancer. The current study explores the …
A macrolide from Streptomyces sp. modulates apoptosis and autophagy through Mcl‐1 downregulation in human breast cancer cells
Secondary metabolites in marine organisms exhibit various pharmacological activities
against diseases, such as cancer. In this study, the anti‐proliferative effect of JBIR‐100, a …
against diseases, such as cancer. In this study, the anti‐proliferative effect of JBIR‐100, a …
Targeting autophagy to enhance chemotherapy and immunotherapy in oral cancer
X Zeng, Y Chen, J Wang, M He, J Qiu… - Frontiers in …, 2025 - frontiersin.org
Oral cancer is a highly malignant disease characterized by recurrence, metastasis, and poor
prognosis. Autophagy, a catabolic process induced under stress conditions, has been …
prognosis. Autophagy, a catabolic process induced under stress conditions, has been …