[HTML][HTML] MicroRNAs as Promising Therapeutic Agents Against Prostate Cancer Resistant to Castration—Where Are We Now?
M Ferreira, M Morais, R Medeiros, AL Teixeira - Pharmaceutics, 2024 - mdpi.com
MicroRNAs are a conserved class of small, tissue-specific, non-coding RNAs that regulate
gene expression to preserve cellular homeostasis. Proper miRNA expression is crucial for …
gene expression to preserve cellular homeostasis. Proper miRNA expression is crucial for …
Applications of advances in mRNA-based platforms as therapeutics and diagnostics in reproductive technologies
WS Bafleh, HMR Abdulsamad… - Frontiers in Cell and …, 2023 - frontiersin.org
The recent COVID-19 pandemic led to many drastic changes in not only society, law,
economics, but also in science and medicine, marking for the first time when drug regulatory …
economics, but also in science and medicine, marking for the first time when drug regulatory …
Comprehensive computational analysis of differentially expressed miRNAs and their influence on transcriptomic signatures in prostate cancer
FM Aldakheel, H Alnajran, A Mateen… - Scientific Reports, 2025 - nature.com
Prostate cancer presents a major health issue, with its progression influenced by intricate
molecular factors. Notably, the interplay between miRNAs and changes in transcriptomic …
molecular factors. Notably, the interplay between miRNAs and changes in transcriptomic …
Potential Biomarkers for Parkinson Disease from Functional Enrichment and Bioinformatic Analysis of Global Gene Expression Patterns of Blood and Substantia Nigra …
The Parkinson disease (PD) is the second most common neurodegenerative disorder
affecting the central nervous system and motor functions. The biological complexity of PD is …
affecting the central nervous system and motor functions. The biological complexity of PD is …
Analysing DNA methylation and transcriptomic signatures to predict prostate cancer recurrence risk
FM Aldakheel, H Alnajran, SA Alduraywish, A Mateen… - Discover Oncology, 2025 - Springer
Prostate cancer (PCa) remains a significant global health challenge, with approximately 1.6
million new cases and 366,000 deaths annually. Despite high survival rates for localized …
million new cases and 366,000 deaths annually. Despite high survival rates for localized …
Computational Analysis of Differentially Expressed Circulating MicroRNA and Identification of Key Genes in Prostate Cancer
Bioinformatics is considered a powerful tool to investigate and deeply analyze large
datasets. A significant quantity of data is generated by prostate cancer and dysregulation of …
datasets. A significant quantity of data is generated by prostate cancer and dysregulation of …
Common Genetic Factors and Pathways in Alzheimer's Disease and Ischemic Stroke: Evidences from GWAS
W Dong, Y Huang - Genes, 2023 - mdpi.com
Alzheimer's disease (AD) and ischemic stroke (IS) are common neurological disorders, and
the comorbidity of these two brain diseases is often seen. Although AD and IS were …
the comorbidity of these two brain diseases is often seen. Although AD and IS were …
[HTML][HTML] MiR-455-3p mediates PPARα through UBN2 to promote apoptosis and autophagy in acute myeloid leukemia cells
Y Xie, L Tan, K Wu, D Li, C Li - Experimental Hematology, 2023 - Elsevier
Acute myeloid leukemia (AML) is one of the deadliest hematologic malignancies, and its
targeted therapy has developed slowly. The molecular mechanism of the pathophysiology of …
targeted therapy has developed slowly. The molecular mechanism of the pathophysiology of …