Exosomes or small extracellular vesicles are considered a new generation of bioinspired-
nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes …

Macrophages are heterogeneous cells that present as different functional phenotypes due to
their plasticity. They can be classified into two categories, namely M1-and M2-like …

The immunosuppressive tumor microenvironment (TME) represents a major barrier for
effective immunotherapy. Tumor-associated macrophages (TAMs) are highly heterogeneous …

Prostate cancer stem cells (PCSCs) play a critical role in prostate cancer progression and
metastasis, which remains an obstacle for successful prostate cancer treatment. Tumor …

Simple Summary Ovarian cancer is a highly lethal female malignancy with high rates of
advanced stage and recurrent disease. Ovarian cancer is characterized as poorly …

Ovarian cancer (OvCA) accounts for one of the leading causes of death from gynecologic
malignancy. Despite progress in therapy improvements in OvCA, most patients develop a …

Tumor associated macrophages in the tumor microenvironment secrete multiple cytokines,
which regulate cancer cells growth and invasiveness. We systematically studied the role of …

Myeloid-derived suppressor cells (MDSCs) constitute a vast population of immature myeloid
cells implicated in various conditions. Most notably, their role in cancer is of great …

Macrophages are the most important innate immune cells that participate in various
inflammation-related diseases. Therefore, macrophage-related pathological processes are …

Tumor vasculature is characterized by aberrant structure and function, resulting in immune
suppressive profiles of tumor microenvironment through limiting immune cell infiltration into …