Malaria parasite centrins can assemble by Ca2+-inducible condensation

Y Voß, S Klaus, NP Lichti, M Ganter, J Guizetti - PLoS Pathogens, 2023 - journals.plos.org
Centrins are small calcium-binding proteins that have a variety of roles and are universally
associated with eukaryotic centrosomes. Rapid proliferation of the malaria-causing parasite …

Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1

H Pan, Y Qin, J Zhu, W Wang, Z Liu, X Huang… - Developmental Cell, 2023 - cell.com
As evolutionarily conserved organelles, lipid droplets (LDs) carry out numerous functions
and have various subcellular localizations in different cell types and species. In avian cone …

Focus on centrin in normal and altered human spermatozoa

E Moretti, D Noto, R Corsaro… - Systems Biology in …, 2023 - Taylor & Francis
This review provides details on the role of centrin in human spermatozoa and in various
forms of male infertility. Centrin is a calcium (Ca2+)-binding phosphoprotein that is located in …

[HTML][HTML] Elucidating the Spatio-Temporal dynamics of the Plasmodium falciparum basal complex

AA Morano, I Ali, JD Dvorin - PLoS pathogens, 2024 - journals.plos.org
Asexual replication of Plasmodium falciparum occurs via schizogony, wherein 16–36
daughter cells are produced within the parasite during one semi-synchronized cytokinetic …

INF2 formin variants linked to human inherited kidney disease reprogram the transcriptome, causing mitotic chaos and cell death

L Labat-de-Hoz, L Fernández-Martín, I Correas… - Cellular and Molecular …, 2024 - Springer
Mutations in the human INF2 gene cause autosomal dominant focal segmental
glomerulosclerosis (FSGS)—a condition characterized by podocyte loss, scarring, and …

Rapid kinetics of calcium dissociation from plant calmodulin and calmodulin-like proteins and effect of target peptides

F Troilo, M Pedretti, C Travaglini-Allocatelli… - Biochemical and …, 2022 - Elsevier
Abstract Calcium (Ca 2+) signaling represents a universal information code in plants,
playing crucial roles spanning developmental processes to stress responses. Ca 2+ signals …

Analysis of Predicted Amino Acid Sequences of Diatom Microtubule Center Components

DP Petrova, AA Morozov, NA Potapova… - International Journal of …, 2023 - mdpi.com
Diatoms synthesize species-specific exoskeletons inside cells under the control of the
cytoskeleton and microtubule center. Previous studies have been conducted with the …

Conformational Plasticity of Centrin 1 from Toxoplasma gondii in Binding to the Centrosomal Protein SFI1

L Bombardi, F Favretto, M Pedretti, C Conter… - Biomolecules, 2022 - mdpi.com
Centrins are calcium (Ca2+)-binding proteins that are involved in many cellular functions
including centrosome regulation. A known cellular target of centrins is SFI1, a large …

Charting the landscape of cytoskeletal diversity in microbial eukaryotes

F Mikus, AR Ramos, H Shah, M Olivetta, S Borgers… - bioRxiv, 2024 - biorxiv.org
Microbial eukaryotes are small and often resistant to standard labelling and imaging
techniques, and therefore remain understudied-despite their critical ecological importance …

[PDF][PDF] Ca2+-inducible phase separation of centrins in proliferating malaria parasites

Y Voß, S Klaus, M Ganter, J Guizetti - bioRxiv, 2022 - scholar.archive.org
Centrins are universally involved in eukaryotic cell division, but their precise mode of
function remains unclear. They are small calcium-binding proteins and a conserved …