[HTML][HTML] Spectrum and Prevalence of Rare APOE Variants and Their Association with Familial Dysbetalipoproteinemia

AV Blokhina, AI Ershova, AV Kiseleva… - International Journal of …, 2024 - mdpi.com
Familial dysbetalipoproteinemia (FD) is a highly atherogenic, prevalent genetically based
lipid disorder. About 10% of FD patients have rare APOE variants associated with autosomal …

[HTML][HTML] Correlation Between Hyperlipidemia-Related Diseases and Thorax/Thigh Circumference Ratio Along with Body Condition Score in Dogs Focusing on …

K Choi - Life, 2024 - mdpi.com
There are some limitations to using the body condition score (BCS) for client education to
prevent obesity, hyperlipidemia-related diseases, and orthopedic diseases in dogs because …

[HTML][HTML] Review of p.(Val429Met), a Variant of LDLR That Is Associated with Familial Hypercholesterolemia

EF Jotch, MS Kindy - Cardiogenetics, 2024 - mdpi.com
Patients affected by familial hypercholesterolemia possess elevated low-density lipoprotein
cholesterol and therefore have greater risk for cardiovascular disease. About 90% of familial …

[HTML][HTML] Improved Genetic Characterization of Hypercholesterolemia in Latvian Patients with Familial Hypercholesterolemia: A Combined Monogenic and Polygenic …

I Atava, M Briviba, G Nesterovics, V Saripo… - International Journal of …, 2024 - mdpi.com
Despite the implementation of next-generation sequencing-based genetic testing on
patients with clinical familial hypercholesterolemia (FH), most cases lack complete genetic …

Impact of 12-SNP and 6-SNP Polygenic Scores on Predisposition to High LDL-Cholesterol Levels in Patients with Familial Hypercholesterolemia

G Cardiero, M Ferrandino, IL Calcaterra, G Iannuzzo… - Genes, 2024 - mdpi.com
Background: Familial hypercholesterolemia (FH) comprises high LDL-cholesterol (LDL-c)
levels and high cardiovascular disease risk. In the absence of pathogenic variants in …

[HTML][HTML] The Importance of Genetic Testing for Familial Hypercholesterolemia: A Pediatric Pilot Study

AT Constantin, C Delia, LM Roșu, I Roșca, I Streață… - Medicina, 2024 - mdpi.com
Background and Objectives: Familial hypercholesterolemia (FH) is a genetic disease that is
massively underdiagnosed worldwide. Affected patients are at high risk of cardiovascular …

Aspects of cardiovascular risk stratification and management of familial hypercholesterolaemia

M Page - 2024 - research-repository.uwa.edu.au
Familial hypercholesterolaemia (FH) causes cardiovascular disease from a young age, due
to extremely high plasma concentrations of LDL-cholesterol. This thesis examines (1) the …

[PDF][PDF] Case Report: Alirocumab Resistance in a Patient with Arteriosclerotic Cardiovascular Disease and Hepatic Dysfunction

S Jin - Ann Clin Med Case Rep, 2024 - acmcasereport.org
1. Introduction: Patients with Alirocumab resistance has not been confirmed in the current
literature. 1.2. Case Report: We reported case of Alirocumab resistance with CAD and …