Colorectal cancer (CRC) is among the top three cancer with higher incident and mortality
rate worldwide. It is estimated that about over than 1.1 million of death and 2.2 million new …

ATP is required for mammalian cells to remain viable and to perform genetically
programmed functions. Maintenance of the ΔG′ ATP hydrolysis of− 56 kJ/mole is the …

Objective To examine the effect of pSer9-GSK-3β on breast cancer and to determine
whether the underlying metabolic and immunological mechanism is associated with …

Internal and external respiration (mt) Mitochondrial catabolic respiration JkO2 is the O2
consumption in the oxidation of fuel substrates (electron donors) and reduction of O2 …

The relative contribution of mitochondrial respiration and subsequent energy production in
malignant cells has remained controversial to date. Enhanced aerobic glycolysis and …

In recent decades, there have been several models describing the relationships between
the cytoskeleton and the bioenergetic function of the cell. The main player in these models is …

Exploring metabolism in human tumors at the cellular level remains a challenge. The
reduced form of metabolic cofactor NAD (P) H is one of the major intrinsic fluorescent …

As the knowledge base and importance of mitochondrial physiology to human health
expands, the necessity for harmonizing the terminology concerning mitochondrial …

Mitochondria perform a central role in life and death of the eukaryotic cell. They are major
players in the generation of macroergic compounds and function as integrated signaling …

Abstract Purpose: Encorafenib+ cetuximab (E+ C) is an effective therapeutic option in
chemorefractory BRAF V600E metastatic colorectal cancer (mCRC). However, there is a …