Progress in electrospun fibers for manipulating cell behaviors

Y Liu, Q Guo, X Zhang, Y Wang, X Mo, T Wu - Advanced Fiber Materials, 2023 - Springer
The manipulation of cell behaviors is essential to maintaining cell functions, which plays a
critical role in repairing and regenerating damaged tissue. To this end, a rich variety of tissue …

Tailoring biomaterials for biomimetic organs-on-chips

L Sun, F Bian, D Xu, Y Luo, Y Wang, Y Zhao - Materials Horizons, 2023 - pubs.rsc.org
Organs-on-chips are microengineered microfluidic living cell culture devices with
continuously perfused chambers penetrating to cells. By mimicking the biological features of …

Recent advances in PLGA-based nanofibers as anticancer drug delivery systems

MS Razavi, A Abdollahi, A Malek-Khatabi… - Journal of Drug Delivery …, 2023 - Elsevier
Polymeric nanofibers (NFs) as biocompatible and biodegradable scaffolds have been
investigated in numerous biomedical fields such as cancer treatment and drug delivery …

Cross-linked electrospun pH-sensitive nanofibers adsorbed with Temporin-Ra for promoting wound healing

F Koohzad, A Asoodeh - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Bioresponsive nanodrug delivery systems have excellent potential in tissue engineering
applications. Poly-anionic and poly-cationic biopolymers have provided a superior platform …

[HTML][HTML] Basement membrane properties and their recapitulation in organ-on-chip applications

G Salimbeigi, NE Vrana, AM Ghaemmaghami… - Materials Today Bio, 2022 - Elsevier
Drug discovery and toxicology is a complex process that involves considerable basic
research and preclinical evaluation. These depend highly on animal testing which often fails …

Large-Scale Fabrication of Freestanding Polymer Ultrathin Porous Membranes for Transparent Transwell Coculture Systems

Y Gao, M Zhong, J Yu, Z Zhao, C Yu, Q Yu, F Yao, J Li… - ACS …, 2024 - ACS Publications
Advancements in cell coculture systems with porous membranes have facilitated the
simulation of human-like in vitro microenvironments for diverse biomedical applications …

[HTML][HTML] Engineering porous membranes mimicking in vivo basement membrane for organ-on-chips applications

J Youn, DS Kim - Biomicrofluidics, 2022 - pubs.aip.org
Porous membrane-based microfluidic chips are frequently used for developing in vitro tissue-
barrier models, the so-called tissue barriers-on-chips (TBoCs). The porous membrane in a …

[HTML][HTML] Recent advances in biofabricated gut models to understand the gut-brain axis in neurological diseases

H Han, J Jang - Frontiers in Medical Technology, 2022 - frontiersin.org
Increasing evidence has accumulated that gut microbiome dysbiosis could be linked to
neurological diseases, including both neurodegenerative and psychiatric diseases. With the …

Recent Progress in Fabrication of Electrospun Nanofiber Membranes for Developing Physiological In Vitro Organ/Tissue Models

D Kim, J Youn, J Lee, H Kim… - Macromolecular …, 2023 - Wiley Online Library
Nanofiber membranes (NFMs), which have an extracellular matrix‐mimicking structure and
unique physical properties, have garnered great attention as biomimetic materials for …

Tunable In Situ Synthesis of Ultrathin Extracellular Matrix‐Derived Membranes in Organ‐on‐a‐Chip Devices

JD Newton, Y Song, S Park… - Advanced …, 2024 - Wiley Online Library
Thin cell culture membranes in organ‐on‐a‐chip (OOC) devices are used to model a wide
range of thin tissues. While early and most current platforms use microporous or fibrous …